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Yukio Maruyama
Researcher at Fukushima Medical University
Publications - 204
Citations - 5091
Yukio Maruyama is an academic researcher from Fukushima Medical University. The author has contributed to research in topics: Heart failure & Coronary circulation. The author has an hindex of 34, co-authored 202 publications receiving 4910 citations. Previous affiliations of Yukio Maruyama include Ohu University & Fukuoka University.
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Attenuation of Ischemia/Reperfusion Injury in Rats by a Caspase Inhibitor
TL;DR: ZVAD-fmk was effective in reducing myocardial reperfusion injury, which could at least be partially attributed to the attenuation of cardiomyocyte apoptosis.
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Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice
Kazunobu Ishikawa,Daisuke Sugawara,Xuping Wang,Kazunori Suzuki,Hiroyuki Itabe,Yukio Maruyama,Aldons J. Lusis +6 more
TL;DR: In this article, mild oxidized LDL markedly induces HO-1 in human aortic endothelial and smooth muscle cell cocultures and that its induction results in the attenuation of monocyte chemotaxis resulting from treatment with mildly oxidised LDL in vitro.
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Bilirubin From Heme Oxygenase-1 Attenuates Vascular Endothelial Activation and Dysfunction
Keiichi Kawamura,Kazunobu Ishikawa,Youichiro Wada,Satoshi Kimura,Hayato Matsumoto,Takahide Kohro,Hiroyuki Itabe,Tatsuhiko Kodama,Yukio Maruyama +8 more
TL;DR: The results suggest that the antiatherogenic properties of HO-1 may be mediated predominantly through the action of bilirubin by inhibition of vascular endothelial activation and dysfunction in response to proinflammatory stresses.
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Apoptosis in relevant clinical situations: contribution of apoptosis in myocardial infarction.
TL;DR: It is controversial whether TUNEL-positive cardiomyocytes in infarcted myocardium are all apoptotic, and progress in investigating the basic mechanisms of apoptosis and recognition of the modes of cardiomeocytes death will contribute to advances in cardioprotective therapy in myocardial infarction.
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Heme Oxygenase-1 Inhibits Atherogenesis in Watanabe Heritable Hyperlipidemic Rabbits
Kazunobu Ishikawa,Daisuke Sugawara,Jun Goto,Yasuyuki Watanabe,Keiichi Kawamura,Masashi Shiomi,Hiroyuki Itabe,Yukio Maruyama +7 more
TL;DR: The results suggest the possibilities that HO-1 has antiatherogenic properties in vivo and that the anti Atherosclerotic properties ofHO-1 are conducted through the prevention of lipid peroxidation.