Yulia Shandalov

TL;DR: A “relay” approach is suggested in which extended in vitro incubation, enabling the formation of a more structured vascular bed, allows for graft-host angiogenic collaboration that promotes anastomosis and vascular integration that supports enhanced muscle regeneration, maturation, and integration.

TL;DR: Understanding is provided regarding the mechanisms whereby VDAC and TSPO may serve as targets to modulate apoptotic rates, which has implications for drug design to treat diseases such as neurodegeneration and cancer.

TL;DR: The use of textured soy protein—an edible porous protein-based biomaterial—as a novel CBM scaffold that can support cell attachment and proliferation to create a 3D engineered bovine muscle tissue is demonstrated.

TL;DR: The described engineered muscle flap, equipped with an autologous vascular pedicle, constitutes an effective tool for reconstruction of large defects, thereby circumventing the need for both harvesting autologously flaps and postoperative scarification.

TL;DR: This study shows that PK 11195 and Ro5 4864 inhibit the pro-apoptotic function of ErPC3 by blocking its capacity to cause a collapse of the mitochondrial membrane potential.