Y
Yung-Hua Li
Researcher at University of Toronto
Publications - 6
Citations - 1894
Yung-Hua Li is an academic researcher from University of Toronto. The author has contributed to research in topics: Biofilm & Streptococcus mutans. The author has an hindex of 6, co-authored 6 publications receiving 1798 citations.
Papers
More filters
Journal ArticleDOI
Natural genetic transformation of Streptococcus mutans growing in biofilms.
TL;DR: It is demonstrated that a peptide pheromone system controls genetic competence in S. mutans and that the system functions optimally when the cells are living in actively growing biofilms.
Journal ArticleDOI
A Quorum-Sensing Signaling System Essential for Genetic Competence in Streptococcus mutans Is Involved in Biofilm Formation
Yung-Hua Li,Nan Tang,Marcelo B. Aspiras,Peter C. Y. Lau,Janet H. Lee,Richard P. Ellen,Dennis G. Cvitkovitch +6 more
TL;DR: It is concluded that the quorum-sensing signaling system essential for genetic competence in S. mutans is important for the formation of biofilms by this gram-positive organism.
Journal ArticleDOI
Quorum sensing and biofilm formation in Streptococcal infections
TL;DR: Members of the bacterial genus Streptococcus are responsible for causing a wide variety of infections in humans, and use quorum-sensing systems to regulate several physiological properties, including the ability to incorporate foreign DNA, tolerate acid, form biofilms, and become virulent.
Journal ArticleDOI
Cell Density Modulates Acid Adaptation in Streptococcus mutans: Implications for Survival in Biofilms
TL;DR: It is demonstrated that cell density and biofilm growth mode modulated acid adaptation in S. mutans, suggesting that optimal development ofacid adaptation in this organism involves both low pH induction and cell-cell communication.
Journal ArticleDOI
Novel Two-Component Regulatory System Involved in Biofilm Formation and Acid Resistance in Streptococcus mutans
Yung-Hua Li,Peter C. Y. Lau,Nan Tang,Gunnel Svensäter,Richard P. Ellen,Dennis G. Cvitkovitch +5 more
TL;DR: A two-component signal transduction system encoded by hk11 and rr11 represents a new regulatory system involved in biofilm formation and acid resistance in S. mutans and is suggested to act as a pH sensor that could cross talk with one or more response regulators.