Quorum sensing and biofilm formation in Streptococcal infections
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Members of the bacterial genus Streptococcus are responsible for causing a wide variety of infections in humans, and use quorum-sensing systems to regulate several physiological properties, including the ability to incorporate foreign DNA, tolerate acid, form biofilms, and become virulent.Abstract:
Members of the bacterial genus Streptococcus are responsible for causing a wide variety of infections in humans. Many Streptococci use quorum-sensing systems to regulate several physiological properties, including the ability to incorporate foreign DNA, tolerate acid, form biofilms, and become virulent. These quorum-sensing systems are primarily made of small soluble signal peptides that are detected by neighboring cells via a histidine kinase/response regulator pair.read more
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Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
Gina Pugliese,Martin S. Favero +1 more
TL;DR: Using tools such as the scanning electron microscope and, more recently, the confocal laser scanning microscope, biofilm researchers now understand that biofilms are not unstructured, homogeneous deposits of cells and accumulated slime, but rather complex communities of surface-associated cells enclosed in a polymer matrix containing open water channels.
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Complete genome sequence of an M1 strain of Streptococcus pyogenes
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TL;DR: The 1,852,442-bp sequence of an M1 strain of Streptococcus pyogenes, a Gram-positive pathogen, has been determined and contains 1,752 predicted protein-encoding genes, consistent with the observation that S. pyogene is responsible for a wider variety of human disease than any other bacterial species.
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Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria
TL;DR: Cell‐density‐dependent gene expression appears to be widely spread in bacteria, and genetic linkage of the common elements involved results in autoregulation of peptide‐pheromone production.