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Yuntao Guan

Researcher at Harbin Veterinary Research Institute

Publications -  43
Citations -  4706

Yuntao Guan is an academic researcher from Harbin Veterinary Research Institute. The author has contributed to research in topics: Virus & Influenza A virus subtype H5N1. The author has an hindex of 23, co-authored 38 publications receiving 3354 citations.

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Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.

TL;DR: The authors' mutagenesis analysis revealed that the amino acid asparagine at position 701 in the PB2 protein was a prerequisite for DKGX/35 transmission in guinea pigs, and an amino acid change in the hemagglutinin (HA) protein was responsible for HA binding to sialylated glycans and was critical for H5N1 virus transmission in Guinea pigs.
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H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet

TL;DR: Transmission studies showed that the H1N1 virus genes encoding acidic polymerase and nonstructural protein made the H5N1irus transmissible by respiratory droplet between guinea pigs without killing them, suggesting that avian H5n1 subtype viruses do have the potential to acquire mammalian transmissibility by reassortment in current agricultural scenarios.
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Replication and virulence in pigs of the first African swine fever virus isolated in China

TL;DR: Results indicate that Pig/HLJ/18 is highly virulent and transmissible in domestic pigs and demonstrates the threat of ASFV and emphasizes the need to control and eradicate ASF in China.