Molecular imprinting technology (MIT), often described as a method of making a molecular lock to match a molecular key, is a technique for the creation of molecularly imprinted polymers (MIPs) with tailor-made binding sites complementary to the template molecules in shape, size and functional groups. Owing to their unique features of structure predictability, recognition specificity and application universality, MIPs have found a wide range of applications in various fields. Herein, we propose to comprehensively review the recent advances in molecular imprinting including versatile perspectives and applications, concerning novel preparation technologies and strategies of MIT, and highlight the applications of MIPs. The fundamentals of MIPs involving essential elements, preparation procedures and characterization methods are briefly outlined. Smart MIT for MIPs is especially highlighted including ingenious MIT (surface imprinting, nanoimprinting, etc.), special strategies of MIT (dummy imprinting, segment imprinting, etc.) and stimuli-responsive MIT (single/dual/multi-responsive technology). By virtue of smart MIT, new formatted MIPs gain popularity for versatile applications, including sample pretreatment/chromatographic separation (solid phase extraction, monolithic column chromatography, etc.) and chemical/biological sensing (electrochemical sensing, fluorescence sensing, etc.). Finally, we propose the remaining challenges and future perspectives to accelerate the development of MIT, and to utilize it for further developing versatile MIPs with a wide range of applications (650 references).

http://ir.yic.ac.cn/bitstream/133337/17045/1/Molecular%20imprinting%20perspectives%20and%20applications.pdf

Molecular imprinting: perspectives and applications

Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).

http://ir.yic.ac.cn/bitstream/133337/4853/1/Recent%20advances%20in%20molecular%20imprinting%20technology%20current%20status%2c%20challenges%20and%20highlighted%20applications.pdf

Recent advances in molecular imprinting technology: current status, challenges and highlighted applications

Herein, we present a survey of the literature covering the development of molecular imprinting science and technology over the years 2004-2011. In total, 3779 references to the original papers, rev ...

Molecular imprinting science and technology: a survey of the literature for the years 2004-2011.

We examine the reversible addition fragmentation chain transfer (RAFT) process with regard to its potential and limits in future industrial applications (including those conducted on a larger scale) as well as materials science. The outlook for the RAFT process is bright: Its unrivaled inherent process simplicity coupled with a wide tolerance to monomer classes and functionalities makes it a prime candidate for the use in large reactors. At the same time, it allows for ready access to complex macromolecular architectures of variable shape and size. © 2008 Wiley Periodicals, Inc.

The future of reversible addition fragmentation chain transfer polymerization

Synthesis and characterization of the core–shell magnetic molecularly imprinted polymers (Fe3O4@MIPs) adsorbents for effective extraction and determination of sulfonamides in the poultry feed

Selective recognition and removal of chlorophenols from aqueous solution using molecularly imprinted polymer prepared by reversible addition-fragmentation chain transfer polymerization.

Selective removal of 2,4-dichlorophenol from contaminated water using non-covalent imprinted microspheres

Selective recognition of veterinary drugs residues by artificial antibodies designed using a computational approach.

Effective removal of rhodamine B from contaminated water using non-covalent imprinted microspheres designed by computational approach

The suitability evaluation of urban human settlements is an important
 foundation to promote the sustainable development of urban human
 settlements. This paper took 11 prefecture-level cities in Hebei Province as
 the research area, and selected 18 indicators from four aspects of
 ecological environment quality, socio-economic status, living conditions,
 infrastructure and public services to construct an evaluation index system
 for the suitability evaluation of the human settlement environment in Hebei
 Province. The fuzzy clustering analysis method was used to divide the
 suitability of the human settlement environment in Hebei Province in 2017.
 The results showed that there are obvious regional differences of human
 settlement environment suitability in Hebei Province, the findings provide
 experience for the sustainable development of human settlement environment
 in Hebei Province.

/pdf/suitability-evaluation-of-urban-human-settlements-based-on-2bizk3fi.pdf

Yuqi Li

Papers

Selective recognition and removal of chlorophenols from aqueous solution using molecularly imprinted polymer prepared by reversible addition-fragmentation chain transfer polymerization.

Selective removal of 2,4-dichlorophenol from contaminated water using non-covalent imprinted microspheres

Selective recognition of veterinary drugs residues by artificial antibodies designed using a computational approach.

Effective removal of rhodamine B from contaminated water using non-covalent imprinted microspheres designed by computational approach

Suitability evaluation of urban human settlements based on fuzzy clustering analysis a case study of Hebei Province