Showing papers in "Biomaterials in 2009"

TL;DR: A fully biological self-assembly approach, which is implemented through a rapid prototyping bioprinting method for scaffold-free small diameter vascular reconstruction and has the ability to engineer vessels of distinct shapes and hierarchical trees that combine tubes of distinct diameters.

TL;DR: It was found that hemolysis and the amount of adhered platelets decreased after alloying for all Mg-1X alloys as compared to the pure magnesium control.

TL;DR: Many of the engineered nanomaterials assessed were found to cause genotoxic responses, such as chromosomal fragmentation, DNA strand breakages, point mutations, oxidative DNA adducts and alterations in gene expression profiles.

TL;DR: Organ printing is a new emerging enabling technology paradigm which represents a developmental biology-inspired alternative to classic biodegradable solid scaffold-based approaches in tissue engineering.

TL;DR: This review presents recent advances in the development of reduction-sensitive biodegradable polymers and conjugates, with particular focus on the up-to-date design and chemistry of various reduction- sensitive delivery systems including liposome, polymersomes, polymeric micelles, DNA containing nanoparticles, polyion complex micells, nano- and micro-gels, nanotubes, and multi-layered thin films.

TL;DR: A water soluble lithium acylphosphinate salt is evaluated for its ability to polymerize diacrylated poly(ethylene glycol) (PEGDA) monomers rapidly into hydrogels, while maintaining high viability during direct encapsulation of cells.

TL;DR: A new class of biocompatible and biodegradable composite hydrogels derived from water-soluble chitosan and oxidized hyaluronic acid upon mixing, without the addition of a chemical crosslinking agent is reported.

TL;DR: The antifungal activity of the silver nanoparticles (NPs) prepared by the modified Tollens process was evaluated for pathogenic Candida spp.

TL;DR: It is concluded that the presence of cellular material within an ECM scaffold modulates the phenotype of the macrophages participating in the host response following implantation, and that the phenotype appears to be related to tissue remodeling outcome.

TL;DR: There is presently not enough scientific data to support the assumption that a simulated body solution (SBF) can be used to test the bioactivity of a material, and the way the test is generally conducted leaves room for improvement.

TL;DR: This essay develops the arguments for a radically different definition of a biomaterial and concludes that many substances which hitherto the authors may not have thought of as biomaterials should now be considered as such so that, alongside the traditional structural biom material, they have substances that have been engineered to perform functions within health care where their performance is directly controlled by interactions with tissues and tissue components.

TL;DR: C cultured rat hippocampus-derived adult NSCs on laminin-coated electrospun Polyethersulfone fiber meshes with average fiber diameters indicated fiber topography can play a vital role in regulating differentiation and proliferation of rNSCs in culture.

TL;DR: In this paper, the combined effect of nanofiber structures and electrical stimulation was examined for rat pheochromocytoma 12 (PC12) cells and hippocampal neurons comparable to noncoated PLGA control meshes.

TL;DR: The data suggest that the PLGA-lecithin-PEG core-shell NPs may be a useful new controlled release drug delivery system.

TL;DR: It is concluded that a combined simultaneous cell and scaffold printing can promote HMVEC proliferation and microvasculature formation.

TL;DR: The importance of substrate stiffness to the proliferation and differentiation of adult NSPCs is demonstrated and the importance of mechanical properties to the success of scaffolds designed to engineer central nervous system tissue is highlighted.

TL;DR: The design of a biomimetic nanofibrous hydrogel as a 3D-scaffold for anchorage-dependent cells may offer an economical model scaffold to3D-culture other anchorage -dependent cells for in-vitro tissue regeneration.

TL;DR: This work describes studies of the proliferation and differentiation of neural stem cells encapsulated within three-dimensional scaffolds--alginate hydrogels--whose elastic moduli were varied over two orders of magnitude.

TL;DR: It is demonstrated that a sequential angiogenic and osteogenic growth factor release may be beneficial for the enhancement of bone regeneration.

TL;DR: The results suggest that organotypic skin tissue culture is feasible using on-demand cell printing technique with future potential application in creating skin grafts tailored for wound shape or artificial tissue assay for disease modeling and drug testing.

TL;DR: 20-nm AuNPs coated with TA-terminated PEG(5000) are promising potential drug delivery vehicles and diagnostic imaging agents and show significantly higher tumor uptake and extravasation from the tumor blood vessels.

TL;DR: These photocrosslinked alginate hydrogels, with tailorable mechanical properties and degradation rates, may find great utility as therapeutic materials in regenerative medicine and bioactive factor delivery.

TL;DR: The initial feasibility and potential of a naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering is demonstrated.

TL;DR: This study indicates rapid freeze-drying technique as an alternative method to fabricate highly interconnected porous scaffolds for developing functional 3D silk fibroin matrices for potential tissue engineering, biomedical and biotechnological applications.

TL;DR: The biomimetic NF-gelatin/apatite scaffolds are excellent for bone tissue engineering and show excellent biocompatibility and mechanical stability.

TL;DR: A targeted drug delivery system that is triggered by changes in pH based on single wall carbon nanotubes, derivatized with carboxylate groups and coated with a polysaccharide material, can be loaded with the anticancer drug doxorubicin (DOX).

TL;DR: In vitro results of the mechanical properties of the TEBVs of the first 25 patients enrolled in an arterio-venous (A-V) shunt safety trial are presented, and these properties are compared with those of risk-matched human vein and artery.

TL;DR: Routine pathological examination and immunohistochemical analysis demonstrated that the Ca-P coating provided magnesium with a significantly good surface bioactivity and promoted early bone growth at the implant/bone interface.

TL;DR: The ability of pCBMA coatings to resist non-specific protein adsorption and significantly retard bacterial biofilm formation makes it a very promising material for biomedical and industrial applications.

TL;DR: The hybridization of AgNPs on clay surface is viable for generating a new class of nanohybrids exhibiting mild cytotoxicity but high efficacy for battling drug-resistant bacteria.