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Yuri Solokhin
Researcher at Russian National Research Medical University
Publications - 1
Citations - 74
Yuri Solokhin is an academic researcher from Russian National Research Medical University. The author has contributed to research in topics: Enhancer & Enhancer RNAs. The author has an hindex of 1, co-authored 1 publications receiving 65 citations.
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Human-specific endogenous retroviral insert serves as an enhancer for the schizophrenia-linked gene PRODH.
Maria Suntsova,Elena Gogvadze,S. V. Salozhin,Nurshat Gaifullin,Fedor M. Eroshkin,Sergey E. Dmitriev,Natalia Y. Martynova,Kirill Kulikov,Galina Malakhova,Gulnur Tukhbatova,Alexey P. Bolshakov,Dmitry Ghilarov,Andrew Garazha,Alexander Aliper,Charles R. Cantor,Yuri Solokhin,Sergey A. Roumiantsev,Pavel M. Balaban,Alex Zhavoronkov,Anton Buzdin +19 more
TL;DR: A systematic, whole-genome analysis of enhancer activity of human-specific endogenous retroviral inserts (hsERVs) identified an element, hsERVPRODH, that acts as a tissue-specific enhancer for the PRODH gene, which is required for proper CNS functioning and is proposed to have contributed to human CNS evolution.