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Anton Buzdin
Researcher at I.M. Sechenov First Moscow State Medical University
Publications - 195
Citations - 5160
Anton Buzdin is an academic researcher from I.M. Sechenov First Moscow State Medical University. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 36, co-authored 170 publications receiving 4088 citations. Previous affiliations of Anton Buzdin include Engelhardt Institute of Molecular Biology & Johns Hopkins University.
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Journal ArticleDOI
Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs.
Marianna A. Zolotovskaia,Maxim Sorokin,Anna A. Emelianova,Nikolay M. Borisov,Denis Kuzmin,Pieter Borger,Andrew Garazha,Anton Buzdin,Anton Buzdin +8 more
TL;DR: Evidence is presented that the MDS algorithm-predicted hits frequently coincide with those already used as targets of the existing cancer drugs, but several novel candidates can be considered promising for further developments.
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Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death
Bridget Larkin,Vladimir Ilyukha,Maxim Sorokin,Anton Buzdin,Edouard Vannier,Alexander Poltorak,Alexander Poltorak +6 more
TL;DR: The first evidence of STING activation in T cells is provided, in which STING agonists not only provoke type I IFN production and IFN-stimulated gene expression, mirroring the response of innate cells, but are also capable of activating cell stress and death pathways.
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Genetics and epigenetics of aging and longevity
TL;DR: The majority of the genes as well as genetic and epigenetic mechanisms that are involved in regulation of longevity are highly interconnected and related to stress response.
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Retroelements and their impact on genome evolution and functioning
Elena Gogvadze,Anton Buzdin +1 more
TL;DR: The up-to-date knowledge of different ways of retroelement involvement in structural and functional evolution of genes and genomes, as well as the mechanisms generated by cells to control their retrotransposition are summarized.
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Human-specific subfamilies of HERV-K (HML-2) long terminal repeats: three master genes were active simultaneously during branching of hominoid lineages.
Anton Buzdin,Svetlana V. Ustyugova,Konstantin Khodosevich,Ilgar Z. Mamedov,Yuri B. Lebedev,Gerhard Hunsmann,Eugene D. Sverdlov +6 more
TL;DR: Using 40 known human-specific LTR sequences, this article derived a consensus sequence for an evolutionary young HERV-K (HML-2) LTR family, which was named the HS family.