Z
Zachary Lipkin-Moore
Researcher at Brandeis University
Publications - 3
Citations - 261
Zachary Lipkin-Moore is an academic researcher from Brandeis University. The author has contributed to research in topics: DNA replication & Homologous recombination. The author has an hindex of 2, co-authored 2 publications receiving 245 citations.
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Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly
John R. Lydeard,Zachary Lipkin-Moore,Yi-Jun Sheu,Bruce Stillman,Peter M. J. Burgers,James E. Haber +5 more
TL;DR: It is shown that BIR requires the replicative DNA helicase (Cdc45, the GINS, and Mcm2-7 proteins) as well as Cdt1, suggesting that origin-independent BIR involves cross-talk between normal DNA replication factors and PRR.
Journal ArticleDOI
Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.
TL;DR: The severe constraint on 5′ to 3′ resection, which also abrogates activation of the Mec1-dependent DNA damage checkpoint, permits an unprecedented level of new telomere addition in sgs1Δ exo 1Δ strains, where the level of BIR is not different from either single mutant.