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Ze-Min Xie
Researcher at Xuzhou Medical College
Publications - 6
Citations - 383
Ze-Min Xie is an academic researcher from Xuzhou Medical College. The author has contributed to research in topics: Neurotrophic factors & Neuropathic pain. The author has an hindex of 6, co-authored 6 publications receiving 284 citations. Previous affiliations of Ze-Min Xie include Nanjing University & Southeast University.
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Journal ArticleDOI
Regulation of glutamate transporter 1 via BDNF-TrkB signaling plays a role in the anti-apoptotic and antidepressant effects of ketamine in chronic unpredictable stress model of depression
Wen-Xue Liu,Jing Wang,Ze-Min Xie,Ze-Min Xie,Ning Xu,Ning Xu,Guang-Fen Zhang,Min Jia,Zhi-Qiang Zhou,Kenji Hashimoto,Jian-Jun Yang,Jian-Jun Yang +11 more
TL;DR: The findings suggest that regulation of GLT-1 on astrocytes, responsible for 90 % of glutamate reuptake from the synapse, through BDNF-TrkB signaling is involved in mediation of the therapeutic effects of ketamine on behavioral abnormalities and morphological changes in the hippocampus of the CUS-exposed rats.
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Spared Nerve Injury Increases the Expression of Microglia M1 Markers in the Prefrontal Cortex of Rats and Provokes Depression-Like Behaviors.
Ning Xu,Ning Xu,Xiao-Hui Tang,Wei Pan,Ze-Min Xie,Guang-Fen Zhang,Mu-Huo Ji,Jian-Jun Yang,Jian-Jun Yang,Mai-tao Zhou,Zhi-Qiang Zhou,Zhi-Qiang Zhou +11 more
TL;DR: It is suggested that SNI can lead to depression-like behaviors, while M1 polarization and consequent overproduction of pro-inflammatory cytokines plays a key role in the pathogenesis of neuropathic pain.
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Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine
Ze-Min Xie,Ze-Min Xie,Xingming Wang,Ning Xu,Ning Xu,Jing Wang,Jing Wang,Wei Pan,Xiao-Hui Tang,Xiao-Hui Tang,Zhi-Qiang Zhou,Zhi-Qiang Zhou,Kenji Hashimoto,Jian-Jun Yang,Jian-Jun Yang +14 more
TL;DR: In this article, the authors examined whether cytokines and brain-derived neurotrophic factor (BDNF) might contribute to individual differences in the development of neuropathic pain-induced depression.
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Role of histone acetylation in long-term neurobehavioral effects of neonatal Exposure to sevoflurane in rats
Min Jia,Wen-Xue Liu,Jiao-Jiao Yang,Ning Xu,Ze-Min Xie,Ling-Sha Ju,Mu-Huo Ji,Anatoly E. Martynyuk,Jian-Jun Yang,Jian-Jun Yang +9 more
TL;DR: Evidence is provided that neonatal exposure to sevoflurane induces neurobehavioral abnormalities and long-lasting alterations in histone acetylation; normalization of histoneacetylation may alleviate the neurodevelopmental side effects of the anesthetic.
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Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model
Guang-Fen Zhang,Jing Wang,Jin-Feng Han,Jie Guo,Ze-Min Xie,Wei Pan,Jian-Jun Yang,Kang-Jian Sun +7 more
TL;DR: In conclusion, acute single dose of ketamine can rapidly attenuate mechanical allodynia and consequent depression-like behaviors and down-regulate hippocampal proinflammatory responses and IDO/KYN signal pathway in rats.