Z
Zerihun T. Dame
Researcher at University of Alberta
Publications - 4
Citations - 3099
Zerihun T. Dame is an academic researcher from University of Alberta. The author has contributed to research in topics: Metabolome & Metabolomics. The author has an hindex of 3, co-authored 3 publications receiving 2687 citations. Previous affiliations of Zerihun T. Dame include National Institute for Nanotechnology.
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Journal ArticleDOI
DrugBank 4.0: shedding new light on drug metabolism
Vivian Law,Craig Knox,Yannick Djoumbou,Timothy Jewison,An Chi Guo,Yifeng Liu,Adam Maciejewski,David Arndt,Michael Wilson,Vanessa Neveu,Alexandra Tang,Geraldine Gabriel,Carol Ly,Sakina Adamjee,Zerihun T. Dame,Beomsoo Han,You Zhou,David S. Wishart +17 more
TL;DR: The latest update of DrugBank, DrugBank 4.0, has been further expanded to contain data on drug metabolism, absorption, distribution, metabolism, excretion and toxicity (ADMET) and other kinds of quantitative structure activity relationships (QSAR) information.
Journal ArticleDOI
The Human Urine Metabolome
Souhaila Bouatra,Farid Aziat,Rupasri Mandal,An Chi Guo,Michael Wilson,Craig Knox,Trent C. Bjorndahl,Ramanarayan Krishnamurthy,Fozia Saleem,Philip B. Liu,Zerihun T. Dame,Jenna Poelzer,Jessica Huynh,Faizath S. Yallou,Nick Psychogios,Edison Dong,Ralf Bogumil,Cornelia Roehring,David S. Wishart,David S. Wishart +19 more
TL;DR: A comprehensive, quantitative, metabolome-wide characterization of human urine and the identification and annotation of several previously unknown urine metabolites and to substantially enhance the level of metabolome coverage are undertaken.
Journal ArticleDOI
The human saliva metabolome
Zerihun T. Dame,Farid Aziat,Rupasri Mandal,Ram Krishnamurthy,Souhaila Bouatra,Shima Borzouie,An Chi Guo,Tanvir Sajed,Lu Deng,Hong Lin,Philip B. Liu,Edison Dong,David S. Wishart,David S. Wishart +13 more
TL;DR: A comprehensive characterization of the human saliva metabolome is presented and multiple analytical platforms including nuclear magnetic resonance spectroscopy, gas chromatography mass spectrometry, direct flow injection/liquid chromatography Mass spectrometer, inductively coupled plasma mass spectromaetry, and high performance liquid chromatography were employed to quantify the metabolites that can be commonly detected in human saliva.
Book ChapterDOI
Discovery of Bioactive Natural Products from Bacillus Species: Chemistry, Biosynthesis and Biological Activities
TL;DR: In this paper , the authors comprehensively review chemistry, biosynthetic pathways, and biological activities of natural products discovered in various strains of Bacillus spp., and discuss their application in biocontrol of plant diseases, medicines, and bioprospecting.