Z
Zev Bryant
Researcher at Stanford University
Publications - 50
Citations - 4677
Zev Bryant is an academic researcher from Stanford University. The author has contributed to research in topics: DNA supercoil & Molecular motor. The author has an hindex of 27, co-authored 46 publications receiving 4219 citations. Previous affiliations of Zev Bryant include University of California, Berkeley & Lawrence Berkeley National Laboratory.
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Journal ArticleDOI
Ten years of tension: single-molecule DNA mechanics
TL;DR: The basic features of DNA were elucidated during the half-century following the discovery of the double helix, but it is only during the past decade that researchers have been able to manipulate single molecules of DNA to make direct measurements of its mechanical properties.
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Structural transitions and elasticity from torque measurements on DNA
Zev Bryant,Michael D. Stone,Jeff Gore,Steven B. Smith,Nicholas R. Cozzarelli,Carlos Bustamante +5 more
TL;DR: Tests of the linearity of DNA's twist elasticity, direct measurements of the torsional modulus, characterization of torque-induced structural transitions, and the establishment of a framework for future assays of torque and twist generation by DNA-dependent enzymes are reported.
Journal ArticleDOI
DNA overwinds when stretched
Jeff Gore,Zev Bryant,Zev Bryant,Marcelo Nollmann,Mai U. Le,Nicholas R. Cozzarelli,Carlos Bustamante +6 more
TL;DR: It is shown that for small distortions, contrary to intuition, DNA overwinds under tension, reaching a maximum twist at a tension of ∼30 pN, and the observed twist–stretch coupling predicts that DNA should also lengthen when overwound under constant tension, an effect that is quantitatively confirmed.
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Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots
Wolfgang J. Parak,Daniele Gerion,Daniela Zanchet,Anke S. Waerz,Christine M. Micheel,Shara C. Williams,Markus Seitz,Richard E. Bruehl,Zev Bryant,Carlos Bustamante,Carolyn R. Bertozzi,Paul Alivisatos +11 more
TL;DR: By using the strategies developed in this study, most biomolecules can be covalently coupled to semiconductor nanocrystals, and these nanocrystal-DNA conjugates promise to be a versatile tool for fluorescence imaging and probing of biological systems.
Journal ArticleDOI
Mechanochemical analysis of DNA gyrase using rotor bead tracking
Jeff Gore,Zev Bryant,Zev Bryant,Zev Bryant,Michael D. Stone,Michael D. Stone,Marcelo Nollmann,Nicholas R. Cozzarelli,Carlos Bustamante +8 more
TL;DR: The activity of gyrase is observed in real time by tracking the rotation of a submicrometre bead attached to the side of a stretched DNA molecule, and rotational pauses corresponding to two kinetic substeps are directly detected.