Zhibo Jiang

TL;DR: Investigation into effects of butyrate on high‐fat diet‐fed ApoE−/− mice after 16 weeks' administration finds no change in the effects of the metabolite on atherosclerosis.

TL;DR: In this paper, BBR attenuated TMA/TMAO production in the C57BL/6J and ApoE KO mice fed with choline-supplemented chow diet, and mitigated atherosclerotic lesion areas in ApOEKO mice.

TL;DR: It is shown that for the production of lidamycin by Streptomyces globisporus that negative feedback can extend to a point higher in the regulatory cascade, and that the feedback to the pleiotropic regulator AtrA is likely to provide a mechanism for coordinating theProduction of lid amycin with that of other secondary metabolites.

TL;DR: The genome sequence of S. globisporus C-1027 will enable us to disclose biosynthetic pathways of these secondary metabolites and discover new natural products with potential applications notably in human health.

TL;DR: SsaX is demonstrated to be responsible for the biosynthesis of m-Tyr in vivo by gene deletion and complementation and indicated that ssaX deletion mutant SS/XKO was a suitable host to expand the diversity of the N-terminus of UPAs, with potential to yield more novel compounds with improved activity and/or other properties.