Z
Zhongkuan Lyu
Researcher at Fudan University
Publications - 2
Citations - 19
Zhongkuan Lyu is an academic researcher from Fudan University. The author has contributed to research in topics: Glymphatic system & Pyroptosis. The author has an hindex of 1, co-authored 2 publications receiving 1 citations.
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Journal ArticleDOI
Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats.
Zhongkuan Lyu,Yuanjin Chan,Qiyue Li,Qiang Zhang,Kaili Liu,Jun Xiang,Xiangting Li,Dingfang Cai,Yaming Li,Bing Wang,Zhong-Hai Yu +10 more
TL;DR: In this paper, the authors used lipopolysaccharide and glycine as the agonist and inhibitor of pyroptosis, respectively, for detecting the detection of pyproptosis and AQP-4, and Aβ1-42 oligomers.
Journal ArticleDOI
Tongxinluo Exerts Inhibitory Effects on Pyroptosis and Amyloid-β Peptide Accumulation after Cerebral Ischemia/Reperfusion in Rats.
TL;DR: In this paper, Tongxinluo (TXL) was used to prevent and treat post-stroke dementia in rats by downregulating expression levels of cleaved caspase-11/1, N-terminal gasdermin D, nucleotide binding oligomerization domain-like receptors pyrin domain containing 3 (NLRP3), interleukin-6 (IL-6), and cleaved IL-1β and abated astrocytic pyroptosis after cerebral I/R.