Synthesis and Characterization of Tetrahedral Ru3O Clusters with Intrinsic Framework Chirality: A Chiral Probe of the Intact Cluster Catalysis Concept†

Synthesis, reaction and enantiomeric resolution of chiral clusters containing SRuNiM (M=Mo, W) core

Novel Rh–Mn mixed-metal carbonyl cluster containing μ3 and μ-bridging carbyne ligands, [(μ3-CC6H5)(μ-CC6H5)Rh2Mn2Cp2(μ-CO)3(CO)3]: structure, electrochemistry and catalytic properties

Study of metal exchange reactions in cobalt containing clusters

Amylose tris(3,5-dimethylphenylcamate) (ADMPC) coated on a kind of small particle silica gel was prepared. On this ADMPC chiral stationary phase (CSP), the direct enantiomeric separation of six novel chiral transition metal tetrahedral clusters has firstly been achieved using n-hexane as the mobile phase containing various alcohols as modifiers. The effect of mobile phase modifiers and the structural variation of the solutes on their retention factors (k) and resolutions (Rs) were investigated. The result suggests that not only the structure and concentration of alcohol in mobile phase, but also the structural differences in racemates can have a pronounced effect on enantiomeric separation. ADMPC-CSP is a suitable CSP for the optical resolution of chiral tetrahedral cluster by HPLC.

Enantioseparation of novel chiral tetrahedral clusters on an amylose tris‐(3,5‐dimethylphenylcarbamate) chiral stationary phase by normal phase HPLC

In order to resolve tetrahedron-type chiral clusters, three chiral clusters containing a functionally substituted
 cyclopentadienyl ligand were prepared, and the reactions of functional substituents were investigated. The ester
 group was hard to hydrolyze while hydrazide can easily condense with the ketonic carbonyl on the cyclopentadienyl
 ring to form a cluster hydrazone. Two optically active auxiliaries have been attached to the chiral framework; however, the diastereoisomers cannot be separated by silica gel chromatography. Their presence was established by 13C NMR spectra.

Zhou Zhong-yuan

Papers

Synthesis and reactions of chiral clusters containing an SRuCoMo core