Z
Zihan Zheng
Researcher at Xi'an Jiaotong University
Publications - 17
Citations - 202
Zihan Zheng is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Inflammation & Chemistry. The author has an hindex of 4, co-authored 10 publications receiving 58 citations.
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Journal ArticleDOI
MiR-145 alleviates Hcy-induced VSMC proliferation, migration, and phenotypic switch through repression of the PI3K/Akt/mTOR pathway
Minghao Zhang,Fan Li,Xiuyu Wang,Jian Gong,Yushan Xian,Guan Wang,Zihan Zheng,Chenxu Shang,Bo Wang,Yanhao He,Weirong Wang,Rong Lin +11 more
TL;DR: Results suggest that miR-145 could inhibit VSMC proliferation, migration, and phenotype switching by preventing activation of the PI3K/Akt/mTOR signaling pathway.
Journal ArticleDOI
HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
Feng Yao,Zhen Hua Jin,Zihan Zheng,Xiaohan Lv,Lingxuan Ren,Jia-Ni Yang,Danli Chen,Bo Wang,Wei Yang,Lifang Chen,Weirong Wang,Jianli Gu,Rong Lin +12 more
TL;DR: Zhang et al. as discussed by the authors investigated the role of Histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.
Journal ArticleDOI
HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
Feng Yao,Zhen Hua Jin,Zihan Zheng,Xiaohan Lv,Lingxuan Ren,Jianjun Yang,Danli Chen,Bo Wang,Wei Yang,Lifang Chen,Weirong Wang,Jianli Gu,Rong Lin +12 more
TL;DR: Zhang et al. as mentioned in this paper investigated the role of Histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.
Journal ArticleDOI
The protective effect of hydroxytyrosol acetate against inflammation of vascular endothelial cells partly through the SIRT6-mediated PKM2 signaling pathway
Feng Yao,Guangde Yang,Yushan Xian,Guan Wang,Zihan Zheng,Zhen Jin,Xie Yundong,Weirong Wang,Jianli Gu,Rong Lin +9 more
TL;DR: Findings indicate that HT-AC regulates the vascular endothelial inflammatory response partly through the TNFRSF1A/SIRT6/PKM2-mediated signaling pathway, and exerts its anti-inflammatory effect partly via the SIRT6-mediated PKM2 signaling pathway.
Journal ArticleDOI
SIRT6 inhibits cholesterol crystal-induced vascular endothelial dysfunction via Nrf2 activation.
Zhen Jin,Yunfang Xiao,Feng Yao,Bo Wang,Zihan Zheng,Hongqian Gao,Xiaohan Lv,Lifang Chen,Yanhao He,Weirong Wang,Rong Lin +10 more
TL;DR: It is found that minute CCs could be endocytosed by endothelial cells (ECs), which then decreased Nitric oxide levels and endothelial nitric oxide synthase activity and expression, upregulated the expression of adhesion molecules and enhanced monocyte adhesion to ECs.