Rong Lin

TL;DR: Zhang et al. as discussed by the authors investigated the role of Histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.

TL;DR: This work provides a general strategy for fabricating BMSCs-encapsulating hydrogel in one step, which has the potential for 3D-printing live cell scaffold for study of vasculogenic differentiation.

TL;DR: In this paper , the authors explored the therapeutic potential of Rha against myocardial injury as well as its underlying mechanisms in vivo and in vitro, and showed that Rha ameliorated mycardial ischaemia and inhibited energy metabolism disorders (NAD+/NADH ratio, ATP, and LD) and oxidative stress (SOD, ROS, etc.).

TL;DR: Wang et al. as mentioned in this paper investigated the role of Sirt6 and Lin28b in vascular endothelial cell pyroptosis and the related mechanism, and showed that Lin 28b expression was upregulated in the aortic intima and aorta of apolipoprotein E knockout (ApoE-/-) mice fed with a high-fat diet (HFD) for 8 or 12 weeks.

TL;DR: Wang et al. as mentioned in this paper investigated the active components of licorice flavonoids that exert anti-atherosclerosis (AS) effects and the underlying mechanisms, and they constructed a compound-target network and screened three active components, namely, isoliquiritigenin (ISL), glabridin, and naringenin in licors.