Showing papers by "Detroit Receiving Hospital published in 1961"
60 citations
TL;DR: The relevance of the lipemic state, per se, to the pathophysiology of myocardial ischemia appears to depend upon the establishment of an oxygen gradient within the myocardium, presumably through altered pressure-flow relationships produced by lipemic blood within a pathologic vessel.
Abstract: The role of the physical state of plasma as a determinant of oxygen availability to the myocardium has been investigated during the course of alimentary lipemia. After the development of substantial plasma lactescence, the coronary blood flow (nitrous oxide method) and myocardial oxygen consumption were assessed in 7 normal human subjects and repeated after heparin-induced lipolysis. The lipemic state was further contrasted with a control fasting group, comparable in age and sex. The mean coronary blood flow for 15 fasting controls was 83 ml. per 100 Gm. of left ventricle per minute with a myocardial oxygen extraction of 11.04 volumes per cent, and a myocardial oxygen consumption of 9.0 ml. per 100 Gm. of left ventricle per minute. By contrast, the mean coronary blood flow during maximal lipemia in the 7 subjects fed cream was 20 per cent below normal, with a value of 67 ml. per 100 Gm. per minute (p=< 0.01). As the extraction of oxygen was not significantly affected, the calculated myocardial oxygen cons...
55 citations
54 citations
TL;DR: It is believed that the modified ferric ammonium chloride reagent along with the extraction procedure described is suitably simple and accurate for the clinical laboratory.
35 citations
28 citations
11 citations
TL;DR: A study was carried out on a new cholesterol reagent which was reported to be a saturated solution of ferrous sulfate in glacial acetic acid and it is suggested that the reactive state of the metal involved is that of the more stable trivalent ferric iron.
Abstract: A study was carried out on a new cholesterol reagent which was reported to be a saturated solution of ferrous sulfate in glacial acetic acid. This solution was shown to be unstable and it is suggested that the reactive state of the metal involved is that of the more stable trivalent ferric iron.
9 citations
8 citations
TL;DR: In each of 60 patients who had bilateral lower third molar extractions, one tooth was removed while the patient was re ceiving enteric-coated trypsin tablets and the second tooth was removal at a later sitting without the use of the enzyme.
Abstract: In each of 60 patients who had bilateral lower third molar extractions, one tooth was removed while the patient was re ceiving enteric-coated trypsin tablets and the second tooth was removed at a later sitting without the use of the enzyme. In the enzyme-treated patients, swelling was considerably less, and dry socket and external ecchymosis were less frequent. There were no side effects from the use of the enzymes. Six tablets on the pre operative day, six tablets on the day of operation, and four tablets on the first postoperative day comprised a satisfac tory dosage.
4 citations
4 citations