Showing papers by "King Faisal Specialist Hospital & Research Centre published in 2006"
TL;DR: The antioxidant activity of S‐carvone obtained from Mentha spicata was evaluated as in vitro using a total antioxidant activity test and indicates that S‐ carvone possess high antioxidant activity compared to α‐tocopherol.
Abstract: S‐Carvone was isolated from Mentha spicata (Fam. Lamiaceae) and purified using chromatographic methods, and also characterized with GS‐MS, FTIR, and NMR techniques. The antioxidant activity of S‐carvone obtained from Mentha spicata was evaluated as in vitro using a total antioxidant activity test. Results were compared with a standard antioxidant, α‐tocopherol. The results indicate that S‐carvone possess high antioxidant activity compared to α‐tocopherol.
92 citations
TL;DR: A rapid, sensitive and reproducible HPLC method was developed and validated for the analysis of haloperidol and its three main metabolites in human plasma.
Abstract: A rapid, sensitive and reproducible HPLC method was developed and validated for the analysis of haloperidol and its three main metabolites in human plasma. The analysis was carried out on a monolithic silica column (Chromolith Performance RP-18e, 100 x 4.6 mm). The mobile phase consisted of sodium phosphate (0.1 m, pH 3.5)-acetonitrile (80:20, v/v) at a flow rate of 2.0 mL/min. UV detection at 230 nm was used, with the detection limits of these compounds ranging from 2 to 5 ng. The separation factors of all studied compounds were in the range 2.30-16.32, while the resolution factors were from 1.00 to 5.37.
28 citations