Institution
Lviv University
Education•Lviv, Ukraine•
About: Lviv University is a education organization based out in Lviv, Ukraine. It is known for research contribution in the topics: Crystal structure & Luminescence. The organization has 3092 authors who have published 4767 publications receiving 33695 citations.
Papers published on a yearly basis
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TL;DR: This work proposes the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard, to facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters.
Abstract: A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.
633 citations
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TL;DR: In this article, in situ powder diffraction of CsPbI 3 and RbPbIsI 3 was performed at a temperature range of 298-687-k and 298-714-k, respectively.
450 citations
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TL;DR: It is reported here that three clustered polyketide synthase genes responsible for rapamycin biosynthesis in Streptomyces hygroscopicus together encode 14 homologous sets of enzyme activities (modules), each catalyzing a specific round of chain elongation.
Abstract: The macrocyclic polyketides rapamycin and FK506 are potent immunosuppressants that prevent T-cell proliferation through specific binding to intracellular protein receptors (immunophilins). The cloning and specific alteration of the biosynthetic genes for these polyketides might allow the biosynthesis of clinically valuable analogues. We report here that three clustered polyketide synthase genes responsible for rapamycin biosynthesis in Streptomyces hygroscopicus together encode 14 homologous sets of enzyme activities (modules), each catalyzing a specific round of chain elongation. An adjacent gene encodes a pipecolate-incorporating enzyme, which completes the macrocycle. The total of 70 constituent active sites makes this the most complex multienzyme system identified so far. The DNA region sequenced (107.3 kbp) contains 24 additional open reading frames, some of which code for proteins governing other key steps in rapamycin biosynthesis.
445 citations
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TL;DR: In this paper, the velocity of nanometric acoustic waves in supercritical fluid argon at high pressures was determined by inelastic X-ray scattering and molecular dynamics simulations, showing that the supercritical region is actually divided into two regions that, although not connected by a first-order singularity, can be identified by different dynamical regimes: gas-like and liquid-like.
Abstract: According to textbook definitions 1 , there exists no physical observable able to distinguish a liquid from a gas beyond the critical point, and hence only a single fluid phase is defined. There are, however, some thermophysical quantities, having maxima that define a line emanating from the critical point, named ‘the Widom line’ 2 in the case of the constant-pressure specific heat. We determined the velocity of nanometric acoustic waves in supercritical fluid argon at high pressures by inelastic X-ray scattering and molecular dynamics simulations. Our study reveals a sharp transition on crossing the Widom line demonstrating how the supercritical region is actually divided into two regions that, although not connected by a first-order singularity, can be identified by different dynamical regimes: gas-like and liquid-like, reminiscent of the subcritical domains.
406 citations
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TL;DR: In this article, the authors map post-socialist farmland abandonment in Western Ukraine using Landsat images from 1986 to 2008, and identify spatial determinants of abandonment using a combination of best-subsets linear regression models and hierarchical partitioning.
363 citations
Authors
Showing all 3127 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rolf Müller | 104 | 905 | 50027 |
Yaroslav Filinchuk | 60 | 301 | 12375 |
Andreas Bechthold | 47 | 185 | 6486 |
Andriy Luzhetskyy | 39 | 163 | 4785 |
I. Sushch | 37 | 109 | 4560 |
Iurii Sushch | 37 | 80 | 3799 |
Yu. Zorenko | 30 | 171 | 3119 |
Marine Elbakidze | 29 | 84 | 2735 |
Arthur Mar | 28 | 313 | 3980 |
Rostyslav Bilyy | 28 | 108 | 3164 |
V. Gorbenko | 26 | 110 | 2175 |
Maksym Yarema | 25 | 64 | 2157 |
Gregory Stryganyuk | 25 | 86 | 2006 |
Leonid Vasylechko | 25 | 185 | 2204 |
Yu. Holovatch | 25 | 153 | 2482 |