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Showing papers in "Acta Tropica in 1988"



Journal Article
Z. Jezek1, Szczeniowski M, K. M. Paluku, M Mutombo, B Grab 
TL;DR: Assessment of the extent of and reasons for clinical diagnostic errors in areas where health staff as well as the general public are aware of human monkeypox shows the presence of lymphadenopathy, pre-eruptive fever and slower maturation of skin lesions are the most important clinical signs supporting correct diagnosis of monkeypox.

88 citations


Journal Article
TL;DR: Reproductive disorders are frequently seen in human beings and in animals infected with tsetse-transmitted (African)trypanosomiasis, and changes are essentially reversible after treatment, although recovery may take several months.

76 citations


Journal Article
TL;DR: Experiments on coprophagy provided the first conclusive demonstration that transmission of T. cruzi occurs between individual Triatoma infestans, as a result of coprophagic behaviour alone, and excluding the possibility of cannibalistic transmission.

51 citations


Journal Article
TL;DR: Although a mouse test may give a broad indication of the sensitivity of a strain, it cannot be used to predict curative doses for cattle, and care should be exercised in extrapolating the results of amouse test to cattle.

49 citations


Journal Article
TL;DR: It is noted, that T. congolense infections that do not respond to treatment with Berenil at 7.0 mg/kg may indicate development of resistance; the use of Samorin at 1.0mg/kg or Homidium may be the alternative.

38 citations


Journal Article
TL;DR: The results show that, whatever the culture medium used, L. infantum behaves in the same way as does L. chagasi, whereas L. mexicana and L. amazonensis display growth patterns similar to that of L. braziliensis.

37 citations


Journal Article
TL;DR: The circumsporozoite precipitation reaction could be induced in sporozoites from either the midGut or the salivary glands 11 days after a blood meal and a similar reactivity of midgut-sporzoites andSalivary gland-sporaozoites was observed with antisporozoites.

28 citations


Journal Article
TL;DR: A high performance liquid chromatographic (HPLC) method for the determination of the antitheilerial drugs parvaqu one and buparvaquone in plasma was developed and was used to elucidate their pharmacokinetics in 6 calves after intramuscular administration.

27 citations


Journal Article
TL;DR: Light and electron microscopic examination showed that the isolated schizonts from lymphoblastoid cells infected with T. parva (Muguga) retained their normal morphology and were essentially free from host cell components.

26 citations


Journal Article
TL;DR: A 12-month field and laboratory study was carried out to determine the epidemiology, clinical features, and transmission dynamics of bancroftian filariasis in the Igwun Basin, Nigeria as discussed by the authors.

Journal Article
TL;DR: A wide variation in growth requirements was observed among leishmaniae which permitted the preparation of different minimum culture media for each Leishmania spp and the requirements for differentiation to amastigotes also varied among the species.

Journal Article
TL;DR: The results of blood-meal identifications for 651 Glossina pallidipes from 5 subpopulations near the Kenya coast south of Mombasa, and one, 70 km inland, are presented and there are significant correlations between the proportions of bovid feeds and T. vivax infections.

Journal Article
TL;DR: Fifteen West African Trypanosoma (T.) brucei isolates from man and animals were cyclically transmitted and representatives of the non-gambiense group were sensitive against the trypanolytic factors of normal human serum and expressed a heterogeneous metacyclic antigen profile.

Journal Article
TL;DR: Results are strongly suggestive that the Gal/GalNAc recognition system of the macrophages is involved in the interiorization of T. cruzi.

Journal Article
TL;DR: Serum procollagen-III-peptide concentrations rose significantly after treatment, suggesting release of propeptide previously incorporated without cleavage into tissue collagen, and the combination of these biochemical and immunological parameters may allow assessment of the pathophysiological mechanisms responsible for liver disease in individual patients.

Journal Article
TL;DR: An analytical method has been developed that is more sensitive and specific than existing methods and it is currently being used in evaluating the pharmacokinetics of isometamidium in cattle.

Journal Article
TL;DR: In vitro-produced metacyclic trypanosomes were used to initiate cultures of bloodstream forms and stages infective to mice were produced in cultures of procyclic forms grown with Anopheles gambiae cells in medium consisting of a mixture of 3 volumes of Cunningham's medium and 1 volume of Anophele cell medium.


Journal Article
TL;DR: An entomological survey based on collections of human bait mosquitoes and of mosquito larvae was carried out through one year in a rice-field, the Kou Valley of southwest Burkina Faso, finding that rice cultivation does not explain however entirely the ecology of mosquito populations.

Journal Article
TL;DR: Parasitological and immunoscreening at the end of 2 years showed that the presence of mf ES antigen in blood correlated with the appearance of microfilariae in blood, suggesting further treatment and follow-up of patients.

Journal Article
TL;DR: The monoclonal antibody had a marked, specific suppression of the cyclical development of T. b.

Journal Article
TL;DR: In malaria patients, plasma concentrations of active and total sulfadoxine were even higher in nonresponders as compared to the subjects who could be successfully cured, while in healthy volunteers there was no increase of the amount of metabolites in plasma.

Journal Article
TL;DR: La diminution de the production of HDL du malade, qui pourrait etre due a la malnutrition ou sous controle genetique, pourrait avoir joue un role capital dans l'etablissement d'une souche de T. brucei isole.

Journal Article
TL;DR: The results showed that the infection of the pathogenic Trypanosoma species became better established in some t setse species than in others, and releases of sterile male tsetse in the tsets control programme will potentially increase the risk of trypanosomiasis during the period of tsete releases in the affected areas.

Journal Article
TL;DR: It is concluded that clinical tolerance is correlated with residual fertility, i.e., the greater the tolerance the higher the retention of fertility.

Journal Article
TL;DR: It is recommended that low-dose corticosteroids be administered in conjunction with DEC--after onset of the Mazzotti reaction--and that they be tapered rapidly.

Journal Article
TL;DR: In 15 patients with Mediterranean spotted fever (MSF), the peripheral blood lymphocyte populations were quantified using monoclonal antibodies that recognize CD3+, CD4+, CD8+, CD38+ and CD20+ cells and a reversal in the normal ratio of T lymphocyte helper-inducer/suppressor-cytotoxic subsets was detected.

Journal Article
TL;DR: Fourth-stage larvae (L4) of the cattle filarial parasite Onchocerca lienalis were produced from third stage forms and maintained in vitro using a variety of culture media and feeder cell layers and the viability was reduced under these conditions.

Journal Article
TL;DR: The results illustrate the potential utility of the double antibody sandwich ELISA for diagnosis of African sleeping sickness and give a better indication of the disease progression than the PATT, especially during trypanocidal drug therapy.