•Journal•ISSN: 2352-8737
Alzheimer's & Dementia: Translational Research & Clinical Interventions
Elsevier BV
About: Alzheimer's & Dementia: Translational Research & Clinical Interventions is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Dementia & Medicine. It has an ISSN identifier of 2352-8737. It is also open access. Over the lifetime, 603 publications have been published receiving 15262 citations. The journal is also known as: TRCI & Alzheimers Dement (N Y).
Topics: Dementia, Medicine, Cognitive decline, Cognition, Disease
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TL;DR: An overview of inflammation in AD is provided and a detailed coverage of a number of microglia‐related signaling mechanisms that have been implicated in AD are reviewed.
1,088 citations
TL;DR: Treatments for Alzheimer's disease (AD) are needed due to the growing number of individuals with preclinical, prodromal, and dementia forms of AD.
603 citations
TL;DR: Study of the AD drug development pipeline can provide insight into the evolution of drug development and how best to optimize development practices.
523 citations
TL;DR: There is an urgent need to develop new treatments for Alzheimer's disease (AD) and to understand the drug development process for new AD therapies.
340 citations
TL;DR: An overall theme of the article is that the process is sufficiently long, complex, and expensive so that many biological targets must be considered for every new medicine eventually approved for clinical use and new research tools may be needed to investigate each new target.
307 citations