Showing papers in "European Journal of Organic Chemistry in 2022"

TL;DR: A review of the recent examples exploiting this manifold to generate highly aggressive halogen radicals to activate C(sp3)−H bonds via Hydrogen Atom Transfer (HAT) for synthetic purposes can be found in this article .

TL;DR: In this paper , the most relevant classes of molecular photoswitches are discussed and a selection of photochromic polymers, gels, porous materials, surfaces, energy-storing materials and other systems triggered with visible light.

TL;DR: A review of the latest generation of halogen-containing agrochemicals introduced into the market over the past 10 years and describes manufacturing approaches of current halogencontaining development candidates is given in this article .

TL;DR: In this article , the use of mechanical force produced by milling, grinding, or extruding, as an activation technique, provides access to chemical entities of all kinds, including heterocyclic compounds, metal complexes and peptides.

TL;DR: Asymmetric organocatalysis has experienced a long and spectacular way since the early reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small (chiral) organic molecules can catalyze (asymmetric) reactions as mentioned in this paper .

TL;DR: In this paper , a review discusses recent progress in the colorimetric and fluorimetric detection of cyanide by nucleophilic addition or acid-base reactions to different types of receptors by the chemodosimeter approach.

TL;DR: In this paper , a review of the recent advances in dual catalytic systems combining organocatalysis and transition metal catalysis is presented, covering the literature of the last five years.

TL;DR: A summary of the latest progress in the field of transition metal catalyzed bioorthogonal reactions, with a special focus on those triggered by activation of multiple carbon-carbon bonds, can be found in this article .

TL;DR: In this article , the authors highlight recent trends and advances in the construction of multistep chemoenzymatic one-pot cascades to access chiral compounds as well as the different strategies to solve current challenges in the field.

TL;DR: In this article , an operationally facile and high yielding one-pot protocol has been developed for the preparation of pyridines appended with pyrazole via NH linker, which includes SNipso/aza-Diels-Alder reactions in up to 54 % yields starting from 1,2,4-triazine precursors.

TL;DR: In this paper , a Silk fibroin-supported Palladium catalyst (Pd/SF) was used as a catalyst for the Suzuki-Miyaura and Ullmann coupling reactions of aryl chlorides, in H2O/EtOH solvent mixture under atmospheric conditions.

TL;DR: In this article , the authors describe the recent progress and new methodologies in organic synthesis based on the use of various lanthanide metals as efficient reducing agents, radical generators or precursors of Grignard reagents.

TL;DR: In this article , the authors present an overview of mechanochemical C−X/C−H functionalization applications to medicinal chemistry efforts, involving cross-coupling, cross-dehydrogenative coupling, oxidative coupling (via C−H activation pathway), and direct coupling via radical pathway.

TL;DR: In this article , the Lewis acid catalyzed zw-type [3+2] cycloaddition reaction of nitrones with nucleophilic ethylenes has been studied within the Molecular Electron Density Theory.

TL;DR: In this paper , a review of cyclopropane cycloaddition reactions is presented with the optimal reaction conditions and with the best organocatalyst producing the best yield and high stereoselectivity.

TL;DR: In this article , the most recent development of a dual photoredox and cobalt catalysis system with particular attention paid to the mechanistic details and substrate scope is presented. But the authors do not provide a detailed review.

TL;DR: A summary of the recent literatures on dearomative annulation reactions involving nitro(hetero)arenes for the construction of synthetically important polycyclic systems has been described in this paper .

TL;DR: A review of low-cost transition metal-catalyzed Heck couplings covering the literature from 2016 to today can be found in this article , where the Heck reaction for carbon-carbon bond formation is one of the most studied coupling reactions in synthetic organic chemistry.

TL;DR: The enantioselective Povarov reaction is one of the most powerful synthetic strategies to synthesize chiral, highly functionalized 1,2,3,4-tetrahydroquinolines as discussed by the authors .

TL;DR: In this paper , the applicability of cooperative [M]-/Organo-catalytic systems in aerobic Si−H-functionalization was investigated and a thorough kinetic study allowed us to identify two complementary catalytic systems based on earth-abundant [m]-catalysts and inexpensive commercially available organic catalysts.

TL;DR: In this paper , a combination of gas phase infrared spectroscopy and first-principles theory was used to characterize the structure of the intermediate of the glycosylation reaction.

TL;DR: A review of the experimental and synthetic history of three classic antiaromatic cores: cyclobutadiene, borole, and pentalene is presented in this article .

TL;DR: In this article , a review of the field of organocatalytic dynamic kinetic resolutions (DKRs) is presented, divided into six sections, according to the different types of organometalysts employed in these reactions, such as Brønsted acid catalysts, hydrogen bonding catalysts and N-heterocyclic carbene catalysts.

TL;DR: In this paper , a Lewis acid-catalyzed (3+2) cycloaddition of 2-indolylmethanols with β,γ-unsaturated α-ketoesters was established, which afforded a series of cyclopenta[b]indoles in overall high yields (up to 98 %) with excellent diastereoselectivities.

TL;DR: In this article , a review highlights the improvement that diversity-oriented synthesis has received from chemoinformatics, presenting recent articles (published between 2016 and 2021) in which DOS libraries are analysed by chemoin-formatics tools, which can assist organic chemists in identifying biologically-relevant regions of the chemical space not yet explored.

TL;DR: In this paper , the role of various catalysts, such as from metal-catalysts to organocatalysts, under different conditions to synthesize various halocyclized products is discussed.

TL;DR: In this paper , the authors discuss cases where selection of the irradiation mode, light intensity (one-, two- photons) or wavelength (UV, blue, green) has a crucial role on the outcome of the photocatalytic event.

TL;DR: In this article , C(sp3)-H functionalization of inert alkanes and visible-light promoted oxidation decarboxylation of N-hydroxyphthalimide (NHP)-esters to access polycyclic quinazolinones have been described.

TL;DR: The use of stable azidobenziodoxoles as useful azidating reagents that allow selective direct azidation of C−H bonds or double carbon-carbon bonds under mild reaction conditions is discussed in this article .