Showing papers in "Experimental Cell Research in 1958"
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TL;DR: A simple method is given for modifying ascites cells, i.e., modifying the cell membrane so that it becomes permeable to large molecules such as nigrosin.
400 citations
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243 citations
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TL;DR: The adhesion and cessation of activity of a leading ruffled membrane appear to be the visible expression of the contact inhibition previously reported, and little or no adhesion or change in surface activity, or in locomotion, can be seen in a sarcoma cell when it meets another, or meets a Fibroblast, or conversely in a fibroblast when it met a sarComa cell.
240 citations
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192 citations
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178 citations
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TL;DR: A mechanism for pinocytosis is suggested which relates adsorption of charged solutes on the plasmalemma to a decrease in the tension and the structural rigidity of the membrane.
164 citations
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TL;DR: Using this procedure, it is shown that in the mouse inductive system consisting of dorsal spinal cord and metanephrogenic mesenchyme, dissociation of either interactant does not destroy its ability to participate in induction.
130 citations
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TL;DR: It is suggested that under unpolarized illumination the subequatorial and peripheral photoreceptors absorb least light primarily because they are by-passed by the cell's focusing action, while under polarized illumination theSubequatorial photoreceptor molecules in the vibration plane absorbs least light because they is periclinally oriented.
129 citations
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TL;DR: Some of the chromosomes of Crepis fixed 5–7 hours after the roots began growing in thymidine-H 3 show a gradient in concentration of tritium with the least amount of the isotope at the ends and an increasing concentration toward the centromere.
125 citations
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TL;DR: A detailed hypothesis is advanced which involves both the binding of protein molecules to the external membrane of the amoeba and the subsequent ingestion of membrane by an active process presumed to be pinocytosis.
120 citations
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TL;DR: It is concluded that dry mass growth is linear for most of each cell generation in the budding yeast Saccharomyces cerevisiae, which lends support to the hypothesis that synthesis is controlled by centres or particles, perhaps microsomal, which remain constant until division.
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TL;DR: A significant decrease in the number of cells lining one side of the crypts of starved rats and the size of the epithelial cell population in starved rats may be explained by an imbalance in the steady state of renewal ofThe epithelium which exists in fed animals.
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TL;DR: Methionine has been incorporated in the unfertilized eggs of Paracentrotus lividus and the distribution of the isotope among cell components has been studied during early development and the possible significance of these results is discussed.
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TL;DR: Amino acid auxotrophs of E. coli, after starvation for their growth factor, do not synthesize nucleic acid, and the calculation of the RNA yield synthesized as a function of the amount of amino acid added suggests that this is a catalytic role.
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TL;DR: It is concluded that the apparent disorganization at the microscopic level does not imply an equally drastic disruption of the underlying organization and the effect of mercaptoethanol is analogized to a “relaxation” or “loosening” of structure that can be reversed almost instantaneously.
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TL;DR: A detailed radioautographic study was made of tissues taken from 12–15 g mice at 8, 24 and 72 hours after adenine-8-C 14 injection, indicating the migration pathway of the newly formed cells.
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TL;DR: Treatment of Sarcoma 37 ascites cells with trypsin was found to be associated with a significant loss of dry mass which was unaccompanied by any appreciable change in the mean cell diameter or the viability of the cells.
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TL;DR: Roughly, the time required for the blocked eggs to complete division when mercaptoethanol is removed is equivalent to the normal time needed for the eggs to pass to division from the stage at which the mercapteethanol was applied.
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TL;DR: It is suggested that in actively dividing cells this is the principal mode of mitochondria formation: other suggested mechanisms are not, however, excluded.
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TL;DR: Une reaction positive avec ce reactif, associee a une reaction metachromatique positive, permet de conclure avec certitude a the presence of polyphosphates.
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TL;DR: The increased microsomal activities during the regeneration period may be conditioned by a higher average concentration of nucleo-protein granules connected with the reticular membranes, which may indicate modified proportions between the granular and lamellar constituents of the endoplasmic reticulum, from which theMicrosomal material emanates.
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TL;DR: The results strongly suggest that the two-dimensional growth is causally connected with the rapid synthesis of protein which is supported by the formation of RNA.