Showing papers in "Human Pathology in 1980"

TL;DR: In this paper, transmission electron microscopy was performed on 12 patients with Crohn's disease and three control subjects to study the immunologic inflammatory response revealed a number of changes of interest, such as degranulation of mast cells and increased number of small dense granules of the arylsulfatase containing type.

TL;DR: The data are interpreted as being strongly supportive of the theory of catecholamine mediation of these myocardial changes in man and of the lethal potential of stress through its effect on the heart.

TL;DR: The localization of type I, III, IV, and AB2 (V) collagens in normal and fibrotic human lungs was studied by indirect immunofluorescence techniques with affinity purified antibodies specific for these types of collagen.

TL;DR: In this article, transmission electron microscopy was used on 12 patients with Crohn's disease and three control subjects to study the autonomic nervous system and smooth muscle changes in the colon.

TL;DR: Indirect immunofluorescence staining of thymic tumors with antikeratin antibody provides a simple, specific, and sensitive method for distinguishing thymoma from lymphoma and seminoma and the method may also prove to be useful in other instances in the distinction between epithelial and nonepithelial tumors.

TL;DR: Preliminary results showed a relationship between the extent of disease and the degree of serum fungistatic activity that was independent of antibody production, and the presence or absence of antirhizopus fungistatics activity and antirHizopus antibody in the sera of six of the patients was correlated with the severity of clinical disease.

TL;DR: A finding that fails to support the hypothesis that vasoconstriction or other nonthrombotic reactions to intravenous drug abuse cause pulmonary hypertension and cor pulmonale is found.

TL;DR: Alveolar proteinosis is described as being a result of poor alveolar clearance in immunosuppressed patients, and forty cases of opportunistic infections and 22 cases of hematologic malignant disease were found among the patients with alveolars proteinosis reported in the literature.

TL;DR: It is concluded that the association of a granuloma with fibrinoid material is highly indicative of Q fever, but serial sections are often necessary to demonstrate this pattern.

TL;DR: Two cases of lymphadenopathy resulting from a lymph node foreign body reaction to silicone are presented and Histologic study in both cases revealed no evidence of malignant disease, but rather demonstrated multinucleated giant cells in reaction to irregular fragments of refractile foreign material.

TL;DR: It is concluded that this skin carcinoma might indeed produce calcitonin, that this tumor may be derived from Merkel cells, and that Merkel cells may belong within the APUD system.

TL;DR: The distribution of rickettsial organisms within the lung indicates that person to person aerosol transmission is extremely unlikely and the effects of the ricksettsial damage to the pulmonary microcirculation are an important component of the pathophysiology of severe Rocky Mountain spotted fever.

TL;DR: Changes in three anatomic barriers--mucus, cell coat, and epithelial cells--found in Crohn's disease are described and a marked increase in cytoplasmic dense vesicles suggests increased losses and increased production of cell coat in diseased areas.

TL;DR: Although early orchiopexy prevents tubular fertility index and mean tubular diameter deterioration due to the noxious effects of temperature in type I testes, it is believed that there is no such benefit in the other types.

TL;DR: An 11 week old female infant with congenitally malformed eyes died from intractable cardiac arrhythmia, and the heart showed extensive oncocytic transformation of myocytes, and this distinctive cardiomyopathy affected the conduction system.

TL;DR: Direct immunofluorescence examination of ear biopsy specimens in both patients showed the presence of granular deposits of immunoglobulins and the C3 component of complement at the chondrofibrous junction, suggesting that immunomicroscopic examination ofEar cartilage could be diagnostically useful in polychondritis.

TL;DR: The mechanism(s) of these sudden fatty liver deaths is unknown as discussed by the authors, however, some attractive theories attribute such deaths to ethanol withdrawal induced hypoglycemia or hypomagnesemia, pulmonary fat embolization from fatty liver, or other facets of the alcohol withdrawal syndrome, including ethanol dependent maladaptive derangements of neurotransmitters.

TL;DR: Patients with congenital heart defects who had or were at risk for developing pulmonary artery hypertension underwent lung biopsy at the time of intracardiac repair, and three grades of severity of early pulmonary vascular changes were identified, which correlated with hemodynamic evidence of progressive functional impairment.

TL;DR: The histologic findings are described in 16 subtotal pancreatectomies performed in patients with hyperinsulinemic hypoglycemia over a 17 year period, finding that patients had nesidioblastosis, defined as the presence of small packets of two to 25 islet cells scattered throughout acinar tissue and separate from islets of Langerhans.

TL;DR: Morphometric analysis of the Liver lesions in patients with various forms of cystic disease of the liver in childhood demonstrates that the entities called the congenital, perinatal, and infantile forms of polycystic disease produce the same liver lesion.

TL;DR: A prominent ultrastructural finding in eight desmoid tumors was myofibroblastic mesenchymal cells with abundant intercellular collagen, and seven of the tumors had intracytoplasmic collagen fibers.

TL;DR: Biopsy specimens from 14 patients with oat cell carcinoma of the lung metastatic to bone marrow and from one patient with a localized tumor were examined for evidence of phagocytic activity by tumor cells.

TL;DR: Clinical, cytogenetic, and autopsy findings are presented in the case of a liveborn female with multiple congenital anomalies mimicking trisomy 18 phenotype, but with partial deletion of the long arms of chromosome 2, region 2, bands 3 and 4.

TL;DR: The resulting theory remains faithful to the laws of physics while explaining the location and distribution of cerebrocortical contusions opposite the site of a moving head impact.

TL;DR: The immune and autoimmune aspects of diabetes mellitus are reviewed and the occurrence of alterations in humoral and cell-mediated immunity, granulocyte function, and the host defense against infectious agents in human diabetics and in animals with experimental diabetes are reviewed.

TL;DR: In a study of 1270 consecutive autopsies there were 314 patients with malignant neoplasms arising in sites other than the kidney and central nervous system, and there was significant renal damage related to cancer.

TL;DR: In this article, the authors present 14 new cases of cytoplasmic hyaline found in patients with a variety of processes causing damage to the alveolar lining; these include cases of radiation pneumonia, diffuse interstitial fibrosis, organizing bacterial pneumonia, as well as asbestosis.