Showing papers in "Journal of Agromedicine in 2007"

Appendix A: informational sources on pesticides and health.

Abstract: http://www.epa.gov/oppfead1/labeling/lrm/ individual chapters of the Pesticide Label Review Manual, 3rd Edition Pesticide Label Review Manual, 3rd Edition. Utilized by the EPA Office of Pesticide Programs (OPP) to improve the quality and consistency of pesticide labels. This document provides guidance on how the US EPA interprets the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and its specific requirements for label language and format. Chapters include: • Precautionary labeling (including Signal Word, Personal Protective Equipment, and First Aid Statements) • Physical or Chemical Hazards • Worker Protection Labeling • Directions for Use • Labeling Claims • Storage and Disposal • Identification numbers (including EPA registration number)

Neurotoxicity of Pesticides

Abstract: Several pesticides such as organophosphates, carbamates and the organochlorine pesticides directly target nervous tissue as their mechanism of toxicity. In several others, such as the fumigants, the nervous system is affected by toxicological mechanisms that diffusely affect most or all tissues in the body. Both the central and peripheral nervous system are involved in the acute toxidromes of many pesticides resulting in acute short-term effects. There is strong human epidemiological evidence for persistent nervous system damage following acute intoxication with several important pesticide groups such as organophosphates and certain fumigants. However, whether persistent nervous system damage follows chronic low-level exposure to pesticides in adults (particularly organophosphpates), and whether in utero and/or early childhood exposure leads to persistent nervous system damage, is a subject of study at present. Parkinson's Disease, one of the most common chronic central nervous system diseases, has been linked to pesticide exposure in some studies, but other studies have failed to find an association. Several new pesticidal chemicals such as the neo-nicotinoids and fipronil have central nervous system effects, but only case reports are available to date on acute human intoxications with several of these. Little data are yet available on whether long-term effects result from these chemicals. Several ongoing or recently completed studies should add valuable insight into the effects of pesticides on the human nervous system particularly the effect of low-dose, chronic exposure both in adults and children.

Reproductive disorders associated with pesticide exposure.

Abstract: Exposure of men or women to certain pesticides at sufficient doses may increase the risk for sperm abnormalities, decreased fertility, a deficit of male children, spontaneous abortion, birth defects or fetal growth retardation. Pesticides from workplace or environmental exposures enter breast milk. Certain pesticides have been linked to developmental neurobehavioral problems, altered function of immune cells and possibly childhood leukemia. In well-designed epidemiologic studies, adverse reproductive or developmental effects have been associated with mixed pesticide exposure in occupational settings, particularly when personal protective equipment is not used. Every class of pesticides has at least one agent capable of affecting a reproductive or developmental endpoint in laboratory animals or people, including organophosphates, carbamates, pyrethroids, herbicides, fungicides, fumigants and especially organochlorines. Many of the most toxic pesticides have been banned or restricted in developed nations, but high exposures to these agents are still occurring in the most impoverished countries around the globe. Protective clothing, masks and gloves are more difficult to tolerate in hot, humid weather, or may be unavailable or unaffordable. Counseling patients who are concerned about reproductive and developmental effects of pesticides often involves helping them assess their exposure levels, weigh risks and benefits, and adopt practices to reduce or eliminate their absorbed dose. Patients may not realize that by the first prenatal care visit, most disruptions of organogenesis have already occurred. Planning ahead provides the best chance of lowering risk from pesticides and remediating other risk factors before conception.

A pilot program using promotoras de salud to educate farmworker families about the risk from pesticide exposure.

Abstract: This paper reviews a successful community-based education effort to minimize pesticide exposure to migrant and seasonal farmworkers and their families through innovative training curricula, informal participatory educational techniques and culturally sensitive outreach methods. In 2004, Migrant Clinicians Network, Inc., trained lay health educators, or promotoras de salud, from local agencies in southern New Mexico in pesticide safety and in ways to successfully promote safety information in the farmworker community. Through home visits and small group workshops, the promotoras trained 273 farmworkers and farmworker family members on ways to reduce exposures to pesticides in their homes and at work, with an emphasis on protecting children. The families received a Spanish language comic book that reinforced the pesticide safety information, emphasizing the health effects of acute and chronic pesticide exposure and steps to protect farmworker children from pesticide exposure. The project resulted in a significant increase in knowledge regarding the routes of exposure, the vulnerability of children, the signs and symptoms of pesticide poisonings and the ways to minimize pesticide exposures. Additionally, the project showed improved behaviors aimed at minimizing pesticide exposure through accidental poisonings in the home. This pilot project proved the efficacy of an in-home, one-on-one approach with a culturally appropriate educational comic book as an instrument to help transfer education to the community. Moreover, the educational method involving promotoras offers a training-of- trainer approach that is easy to implement and potentially replicate.

Summary of documented fatalities in livestock manure storage and handling facilities--1975-2004

Abstract: Data were compiled and analyzed on the estimated frequency and characteristics of deaths related to on-farm manure storage and handling facilities for the period of 1975 through 2004. Sources included published government reports, national and local media, on-line searches, published farm fatality reports, and prior litigation. No prior research was identified that addressed the magnitude of the problem, nor documented evidence-based intervention strategies. Data from 77 fatalities along with 21 severe injuries and 14 international fatality cases were identified, documented and coded for analysis. Analysis of the 77 fatalities showed that victim characteristics and causative factors did not reflect previously reported patterns; i.e., over half of the fatalities involved dairy operations and 21% involved persons under the age of 16. The largest percentage (34%) of deaths occurred to persons conducting repair or maintenance activities on manure handling equipment, while the second largest group (22...

Managing pesticide chronic health risks: U.S. policies.

Abstract: Summary This paper provides an overview of U.S. government pesticide risk management efforts over time and in recent years, relevant to chronic health risks of pesticides. Pesticides are in widespread usage in the U.S. With hundreds of active ingredients and thousands of products on the market, management of pesticide risks has been a daunting challenge. The first legislation providing federal authority for regulating pesticides was enacted in 1910. With the establishment of the U.S. Environmental Protection Agency in 1970 and amendments to the pesticide law in 1972, the federal government was for the first time given the authority to regulate health and environmental risks of pesticides. However, older pesticide risks were not addressed until legislation was enacted in 1988, requiring “reregistration” and 1996, requiring that pesticide food standards are safe for children. In result, the U.S. has seen an expansion of development of pesticide products that are registered as “reduced risk” or are biologica...

Carcinogenicity of agricultural pesticides in adults and children.

Abstract: The role of specific agricultural pesticides in relation to adult and childhood cancers has not been firmly established due to the lack of precise exposure data in previous studies. Improvements in exposure assessment, disease classification, and application of molecular techniques in recent epidemiological evaluations is rapidly improving our ability to evaluate the human carcinogenicity of agricultural pesticides. The role of pesticide exposures in the etiology of human cancer is outlined by anatomical site and recent development in exposure assessment and molecular epidemiology are summarized and evaluated.

Assessing Noise Exposures in Farm Youths

Abstract: Objective: This exploratory study evaluated the feasibility of field exposureassessment methods to characterize the noise sources and levels that farm youthsexperience during a typical workday. Methods: Detailed exposure assessments were performed with a sample of 10 farm youths working on Vermont dairy farms to characterize potential noise hazards typical in the farm setting. Personal and area noise measurements were taken using noise dosimeters. Information concerning work- and non-work-related noise exposure histories was collected via questionnaire. Results: The average age was 15.5 years (SD 2.5, range 10-18). Youths started working at an average age of 8.4 years (SD 2.3, range 6-12) and during the summer months worked an average of 41.3 hours per week (SD 32.3, range 2-68). Two youths exceeded the OSHA action level, having eight-hour time-weighted averages of 95 dBA and 92 dBA, or alternatively, doses of 206% and 127%. (The OSHA action level for the hearing conservation amendment is an eigh...

A task-based assessment of noise levels at a swine confinement.

Abstract: This study describes a task-based noise evaluation conducted at a community college that operated a small swine confinement for training and profit. Seven full-shift dosimeter samples and area noise data were collected during the evaluation. The time weighted average noise levels were all well below the Occupational Safety and Health Administration's (OSHA) Permissible Exposure Limit, but exceeded the National Institute for Occupational Safety and Health's Recommended Exposure Limit on three of seven occasions. The potential for high noise exposures is evidenced in the noise dose measured for specific activities such as power washing, ear clipping, and snout snaring. When the data were extrapolated to depict exposures where specific tasks were carried out over a full shift, tasks such as power washing and snout snaring would exceed the OSHA Action Level (AL). Employees who exceed the OSHA AL are required to be enrolled in a hearing conservation program.

Bronchodilator responsiveness in swine veterinarians.

Abstract: Objective: Swine veterinarians are known to be at risk for respiratory symptoms and airflow obstruction. The present study reassessed the prevalence of respiratory complaints and pulmonary function abnormalities in swine veterinarians and sought to characterize their response to bronchodilators. Methods: A cross-sectional study was conducted during the American Association of Swine Veterinarians annual meeting. Subjects completed a respiratory symptom and workplace exposure history questionnaire and spirometry. Subjects with airflow obstruction were assessed for a post-bronchodilator response with beta 2 agonist administration. Results: Participants included 58 veterinarians (mean age, 45.5 years). Work-related symptoms assessed by questionnaire included rhinitis symptoms (60.3%), cough and chest tightness (55.2%), and wheezing (35.1%). Airflow obstruction was detected in 11/58 (19%) of subjects by spirometry. Only 2/9 (22.2%) met American Thoracic Society criteria for reversibility with bronchod...

Surveillance for pesticide-related disease

Abstract: Public health surveillance for acute pesticide intoxications is discussed. Explanation of the goals, components and functions of population-based surveillance is provided with reference to key informational sources. Both a state-based pesticide intoxication program and a nearly nationwide poison control center data base program are used to illustrate the potential uses inherent in these types of system. There is additional discussion on the investigation of disease clusters, the use of complementary exposure monitoring data and confidentiality issues.

Contact dermatitis in agriculture

Abstract: Summary Dermatitis in agricultural workers, albeit a common entity, infrequently receives scrutiny as to mechanism and prevention. We briefly describe potential mechanisms, examples for each, and offer an algorithm for etiologic diagnoses.

Cutaneous larva migrans in a migrant Latino farmworker.

Abstract: Migrant farmworkers experience a high incidence of skin disease. This report provides information on the case history of cutaneous larva migrans in a Latino migrant farmworker. Treatment options are reviewed, and information for prevention is discussed.