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Showing papers in "Journal of Chronic Diseases in 1973"



Journal ArticleDOI
TL;DR: This paper presents a method for predicting how much change can be expected from regression, and thus a means of estimating the treatment effect, based on measures of within-person and between-person variability.

212 citations


Journal ArticleDOI
TL;DR: For Black males, the younger, overweight High Stress residents had significantly higher Borderline and Hypertensive levels than did a similar Black Low Stress subgroup, and for both groups, being raised in Detroit and not migrating from elsewhere was related to higher readings.

204 citations


Journal ArticleDOI
TL;DR: More of the people with persistent back pain who report limitations in functioning have used health care services compared with others in the sample who also reported functional limitations, presumably resulting from health conditions other than back pain.

163 citations



Journal ArticleDOI
TL;DR: Age-related degenerative changes occurred, such as increasing diameter of the aorta and decreasing creatinine clearance, and the declining ECG voltage with age may be indicative of cardiac disease.

148 citations


Journal ArticleDOI
TL;DR: The overall cumulative survival rate by the life-table method declined to 35 per cent after 7 yr of follow-up and factors associated with significantly reduced survival were: older age, elevated sedimentation rate, anemia, proteinuria and heavy use of alcohol or cigarettes.

124 citations


Journal ArticleDOI
TL;DR: A 5-yr follow-up of 10,059 male government and municipal employees of Israel aged 40 and over revealed a significant variation between the birth-areas in respect of age-adjusted prevalence and incidence rates of myocardial infarction as well as total mortality for all causes.

95 citations


Journal ArticleDOI
TL;DR: Since Smith’s publication, mortality and incidence data for selected Chinese populations in Asia have become available and the literature based on clinical and necropsy series has continued to grow.

86 citations


Journal ArticleDOI
TL;DR: Two IMPORTANT issues in planning and executing a longitudinal study are the frequency of repeated measurements on the subjects and the study duration.

79 citations



Journal ArticleDOI
TL;DR: It is revealed that patients who subjectively experience a long wait when coming to see the doctor, particularly those who feel irritated over this situation tend to be poor compliers with regard to taking medications and continuing to come to the doctor as advised.

Journal ArticleDOI
TL;DR: The principal conclusion is that what counts in the production of MI may not be the amount of situational or intrapsychic stress a person is subjected to but the way he copes with it—is defensive style.

Journal ArticleDOI
TL;DR: It is concluded that it is rarely advisable to discontinue treatment within 1 yr and that long term or even permanent steroid therapy may be necessary to prevent serious complications of the disease.


Journal ArticleDOI
TL;DR: Twenty-eight children with systolic and diastolic blood pressures beyond one standard deviation above the mean of their peer group at age 5 were re-examined at ages 11–12 and compared with sex-matched controls drawn from the original peer group.

Journal ArticleDOI
TL;DR: The widely accepted thesis that MS is an immunologic disease is briefly examined, and discordant evidence is summarized, since this is where clues may be found for incisive future studies of this elusive disease.

Journal ArticleDOI
TL;DR: For the cause-specific analyses, the pattern of mortality was reasonably consistent for each analysis sub-category implying that excess deaths were not solely due to any of these three specific principal causes.


Journal ArticleDOI
TL;DR: Using data on patients hospitalized at the Massachusetts General Hospital, the sex ratio for trigeminal neuralgia was estimated to be 1.17 females: males, and possible risk factors are non-Jewish religion and birth in the United States.

Journal ArticleDOI
TL;DR: The advantages and disadvantages of both biopsy procedures are compared and the relationship of the peripheral blood changes to the frequency of positive marrow biopsy findings is also examined.

Journal ArticleDOI
TL;DR: The method is applicable to the design of experiments to estimate relative risk of disease as well as to trials comparing the efficiency of two treatments, and how to determine sample size when any other regular function of p 1 j and p 2 j can be assumed constant over all k strata.

Journal ArticleDOI
TL;DR: The data provide no evidence of a causal association between analgesic consumption and the subsequent development of impaired renal function, except in the case of females over age 60 yr, where the presence of white blood cells in the urine was associated with increasing duration of daily analgesic use.

Journal ArticleDOI
TL;DR: For the first time in nearly four decades, aortic regurgitation and cardiovascular morbidity occur equally in the 127 surviving syphilitic and control subjects of the long-continuing Tuskegee Study of untreated syphilis.

Journal ArticleDOI
TL;DR: Data coded from death certificates show that the populations studied were different with regard to rates of death from cerebrovascular disease as reported, and a greater frequency of death in Georgia than in the West is consistent with the difference in mortality from cerebral hemorrhage.

Journal ArticleDOI
TL;DR: In this paper, a maximum likelihood estimator of the parameters for a multiple-hit curve which fits best the empirical decay of a population label of circulating platelets is derived, and the model is deterministic with errors of measurement which are normally and independently distributed and with constant variance.

Journal ArticleDOI
TL;DR: The clinical course of patients originally part of a large scale randomized prospective clinical trial of treatment for cancer of the prostate who were later taken off-study and given additional therapy is described, leading to several important observations and inferences.