Showing papers in "Maturitas in 1978"

TL;DR: The incidence of hyperplasia during sequential oestrogen/progestogen therapy is greatly reduced and therefore progestogens are capable of protecting against the development of this condition.

TL;DR: No endometrial malignancies were detected in 2,552 patient years of therapy with estrogens and progestogens and in 1,028 patient-years of observation where estrogens only was the therapy.

TL;DR: Environmental variables that might affect the age at menopause were analysed by means of the segmentation method AID and marital status, occupation, smoking habits, age at last pregnancy and height were shown to be significant discriminating variables.

TL;DR: It is recommended that all women on exogenous estrogen treatment have their blood pressure checked at least once every 6 months, and changes in bodyweight or diastolic blood pressure need not be considered as potential disadvantages in the evaluation of indications for long-term estrogen treatment.

TL;DR: There is evidence that psychological symptoms do occur in increased frequency in relationship to declining ovarian function, and administration of oestrogens alone or in combination with progestogens appear to alleviate some of the symptoms.

TL;DR: A review of the literature from 1864 to 1964 is undertaken, that suggests there may be a secular trend in Denmark, England, France, Germany, Russia and the USA, but must be corroborated by longitudinal, cross cultural, generational research of mothers' and daughters' ages at menopause, or at least, cohort analysis of specific populations.

TL;DR: A double-blind crossover trial of clonidine failed to show any effect of the drug on menopausal vasomotor symptoms, but a significant placebo effect was observed, the effect being greater in those with long-standing symptoms and a high neurotic index.

TL;DR: In this study of 3,682 climacteric women, 340 patients presented with postmenopausal bleeding during an 18-mth period, the incidence of curettage was highest in the untreated women (23.2%), lowest in the estrogen-progestogen users (3.9%) and indicated in 14.2% of those patients receiving estrogens alone.

TL;DR: The results suggest that estriol succinate is devoid of general harmful effects on the renin-aldosterone system during postmenopausal therapy for climacteric symptoms.

TL;DR: Evidence that the intake of synthetic oestrogens such as ethinyl oestradiol has already been found to lead to a disturbance of tryptophan metabolism and to a deficiency of vitamin B6 is found, not only in women taking oestrogen in oral contraceptives but also as replacement therapy during the postmenopause is found.

TL;DR: A relatively low symptomatology was found among European Jews, North African Jews and Arabs in the peri- or postmenopause where their work load was unchanged or somewhat more than before, while the Persian Jews showed a remarkable contrast.

TL;DR: The oestriol concentrations were clearly higher in the beginning or in the middle of the normal menstrual cycle in the fertile woman and the ratio E3/(E2 + E1) was clearly higher than before treatment and during thenormal menstrual cycle.

TL;DR: In both treatment groups the quotient E3/(E2 + E1) was similar to that found at the 6-7th day and in the middle of the normal menstrual cycle, the quotients E1/(E1 + E3) was somewhat higher than during normal cycle.

TL;DR: The effect of long-term oestrogen treatment of at least 5 yr on the development of osteoarthrosis was studied in 48 postmenopausal women and seems to be independent of the hormonal status in post menopausal women.

TL;DR: Psychometric tests showed that as age increased nervousness, emotional lability, aggressive behaviour and tenseness increased in frequency, which is important for the gynaecologist in his pre- and postoperative psychosocial evaluations.

TL;DR: Fifty-three uterine cancer patients who complained of the syndrome dur to vasomotor manifestations or psychosomatic response after ovariectomy were given Premarin tablets, 1.25 mg per day or placebo for 3 weeks and improvement in their complaints was compared from the Psychosomatic aspects by the double-blind method.