Journal•ISSN: 0885-3177
Pancreas
Lippincott Williams & Wilkins
About: Pancreas is an academic journal published by Lippincott Williams & Wilkins. The journal publishes majorly in the area(s): Pancreatitis & Pancreas. It has an ISSN identifier of 0885-3177. Over the lifetime, 6757 publications have been published receiving 160761 citations.
Papers published on a yearly basis
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TL;DR: The categorization of AIP into types 1 and 2 should be helpful for further clarification of the clinical features, pathogenesis, and natural history of these diseases.
Abstract: Objectives:To achieve the goal of developing international consensus diagnostic criteria (ICDC) for autoimmune pancreatitis (AIP).Methods:An international panel of experts met during the 14th Congress of the International Association of Pancreatology held in Fukuoka, Japan, from July 11 through 13,
1,232 citations
TL;DR: Issues in the pathologic assessment of NETs that are common among primaries of different sites are examined and the distinction of well-differentiated from poorly differentiated NETs and the significance of proliferative rate in prognostic assessment are examined.
Abstract: Neuroendocrine tumors (NETs) arise in most organs of the body and share many common pathologic features. However, a variety of different organ-specific systems have been developed for nomenclature, grading, and staging of NETs, causing much confusion. This review examines issues in the pathologic assessment of NETs that are common among primaries of different sites. The various systems of nomenclature are compared along with new proposal for grading and staging NETs. Although differences persist, there are many common themes, such as the distinction of well-differentiated (low and intermediate-grade) from poorly differentiated (high-grade) NETs and the significance of prolif- erative rate in prognostic assessment. A recently published minimum pathology data set is presented to help standardize the information in pathology reports. Although an ultimate goal of standardizing the pathologic classification of all NETs, irrespective of primary site, remains elusive, an understanding of the common themes among the different current systems will permit easier translation of information relevant to prognosis and treatment.
1,014 citations
830 citations
TL;DR: A review of available information on commonly used pancreatic adenocarcinoma cell lines is presented as a resource to help investigators select the cell lines most appropriate for their particular research needs.
Abstract: The dismal prognosis of pancreatic adenocarcinoma (PA) is due in part due to a lack of molecular information regarding disease development. Established cell lines remain a useful tool for investigating these molecular events. Here we present a review of available information on commonly used PA cell lines as a resource to help investigators select the cell lines most appropriate for their particular research needs. Information on clinical history, in vitro and in vivo growth characteristics, phenotypic characteristics, such as adhesion, invasion, migration and tumorigenesis, and genotypic status of commonly altered genes (KRAS, p53, p16, and SMAD4) was evaluated. Identification of both consensus and discrepant information in the literature suggests careful evaluation before selection of cell lines and attention be given to cell line authentication.
775 citations
TL;DR: The incidence of acute pancreatitis seems to be increasing, and the case fatality rate has decreased over time, but the overall population mortality rate per 100,000 has remained unchanged.
Abstract: Objective:To systematically review trends in the epidemiology of the first attack of acute pancreatitis (AP) based on reported population-based studies.Methods:From Medline, we retrieved 18 full-length English language peer-reviewed original articles published from 1966 to June 2005 with population-
620 citations