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Showing papers in "Research Reports in Clinical Cardiology in 2019"


Journal ArticleDOI
TL;DR: An in-depth review sheds light on the most important literature to date on Brugada syndrome, highlighting insights that shifted the global perspective on the disease.
Abstract: Jagdeep Walia Christian Steinberg Zachary Laksman 1Heart Rhythm Services, Division of Cardiology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada; 2Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Universite Laval, Québec, Canada Abstract: Since the first reported descriptions of Brugada syndrome, there has been a growing awareness and appreciation of the disease and its implications. From the diagnostic criteria, to risk stratification and management, there is an ongoing evolution, reclassification and re-thinking of Brugada syndrome as basic science, registry and clinical trial data shape our understanding of the pathophysiology and its clinical implications. This in-depth review sheds light on the most important literature to date, highlighting insights that shifted the global perspective on the disease. Current clinical paradigms and guidelines are presented, along with their justification, and possible opportunities for future research are explored.

6 citations


Journal ArticleDOI
TL;DR: A relative study for two different stent models during implantation in coronary artery is demonstrated to improve the design of the available stent model, and helps in probing the integrity of newly suggested models and reduces certain risks associated with the angioplasty technique.
Abstract: Biomedical Engineering & Sciences Department (BMES), School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology (NUST), Islamabad, Pakistan Introduction and purpose: For the implantation of a small mechanical supporting device such as a stent, angioplasty is a more reliable technique to regain the perfusion along the heart vessel. This researchwork demonstrates a relative study for two different stent models during implantation in coronary artery. The purpose of this analysis was to explore the clinical efficiency of a balloon expandable stent deployment employing the finite element method. Methods: The two different models included are the Cypher Bx Velocity (Bx_Velocity; Johnson & Johnson Corporation, New Brunswick, NJ, USA) and Savior (ST Flex Pro; National Engineering and Scientific Commission, Islambad, Pakistan). As the majority of stents are deployed using an angioplasty balloon guided by a catheter-shaft, in this study, the delivery of stents was governed by a sophisticated balloon of a trifolded pattern, attached to the catheter-shaft. This configuration has often been neglected in the past due to the complexity of interaction and the limitation of computational power. Results: The use of a trifolded semi-compliant balloon gives more promising results for quantification with experimental data available from the manufacturer’s compliance charts. This type of relative study allows us not only to improve the design of the available stent model, but also helps in probing the integrity of newly suggested models and reduces certain risks associated with the angioplasty technique. The following factors, such as stent expansion, foreshortening, dog-boning, elastic recoil, and the distribution of equivalent stresses were used to compare and improve the clinical outcome of the available stent models. Conclusion: The validation of numerical study for the Bx_Velocity stent was made with the manufacturer’s compliance chart data and for the Savior Stent with a report of experimental work data from NESCOM. Finally, some suggestions were made for good deliverability and reliability based on the above design criteria.

6 citations


Journal ArticleDOI
TL;DR: This work is licensed under the Creative Commons Attribution – Non Commercial (unported, v3.0) License and incorporated into the Terms (https://www.dovepress.com/terms.php) by accessing the work.
Abstract: php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). Research Reports in Clinical Cardiology 2019:10 1–6 Research Reports in Clinical Cardiology Dovepress

5 citations


Journal ArticleDOI
TL;DR: This article will focus on the clinical perspectives for CTI-dependent AFL, with radiofrequency catheter ablation representing an efficient strategy with a high success rate and few complications.
Abstract: Department of Cardiology, Princess Grace Hospital, Monaco (Principality), Monaco, Monaco Abstract: The precise circuit of cavotricuspid isthmus (CTI)-dependent atrial flutters (AFLs) has been well characterized, but the recent arrival of ultrahigh-resolution mapping systems has further improved our understanding of this “old” arrhythmia. CTI-dependent AFL may be the arrhythmia for which the electrocardiograph (ECG) correlation with the mechanism may be the highest. Once the diagnosis is made (predominantly based upon the surface ECG), the therapeutic options are precisely defined, with radiofrequency catheter ablation representing an efficient strategy with a high success rate and few complications. This article will focus on the clinical perspectives for CTI-dependent AFL.

3 citations



Journal ArticleDOI
TL;DR: The purpose of this study was to evaluate the effect of a pre-seasonal 12-week warm weather period on sports medicine and Rehabilitation practice in Tartu.
Abstract: 1Institute of Sport Sciences and Physiotherapy, Medical Faculty, University of Tartu, Tartu, Estonia; 2Estonian Centre of Behavioural and Health Sciences, University of Tartu, Tartu, Estonia; 3Department of Cardiology, Institute of Clinical Medicine, Medical Faculty, University of Tartu, Tartu, Estonia; 4Endothelial Centre, University of Tartu, Tartu, Estonia; 5Department of Surgery, Institute of Clinical Medicine, Medical Faculty, University of Tartu, Tartu, Estonia; 6Department of Biochemistry, Institute of Biomedicine and Translational Medicine, Centre of Excellence for Genomics and Translational Medicine, Medical Faculty, University of Tartu, Tartu, Estonia; 7Heart Clinic, Tartu University Hospital, Tartu, Estonia; 8Department of Sports Medicine and Rehabilitation, Institute of Clinical Medicine, Medical Faculty, University of Tartu, Tartu, Estonia; 9Sports Medicine and Rehabilitation Clinic, Tartu University Hospital, Tartu, Estonia Aim: The purpose of this study was to evaluate the effect of a pre-seasonal 12-week

2 citations