Showing papers in "Seminars in Arthritis and Rheumatism in 1972"

TL;DR: Many of the pathways of folate metabolism in patients with rheumatoid arthritis, particularly with regard to dietary requirements, cell proliferation, protein abnormalities, and deficiency of iron and pyridoxine, require further investigation.

TL;DR: It is clear that hyperuricemia has implications far beyond mere gouty arthritis and that it involves a large part of the field of general medicine itself.

TL;DR: The historical development of the long sequence of hypotheses relating to the disposition of uric acid by the kidneys evolved in conjunction with more general concepts intended to explain how the kidney so precisely performs all its diverse and intricate functions.

TL;DR: Similar degrees of abnormality of radioisotope uptake or clearance rate may be found in rheumatoid arthritis, Reiter’s disease, septic arthritis, psoriatic arthritis, acute gouty arthritis, and systemic lupus erythematosus.

TL;DR: The clinical diagnosis of rheumatoid heart disease is based on guilt by association and by exclusion of other common forms of heart disease.

TL;DR: Evidence for the presence of uric acid abnormalities in acromegaly is equivocal, and the hyperuricemia seen post-adrenalectomy is related to the primary hypertensive state rather than to adrenal dysfunction.

TL;DR: In simultaneously aspirated samples of synovial fluid, the level of lysozyme was higher in the more severely involved joints, and appeared to correlate best with the activity of the disease in a particular joint.

TL;DR: It is recognized that although deficient factor replacement, physical therapy, and other orthopedic measures are of utmost importance, optimal care of the child with hemophilia must also include attention to the social and psychological complications of this disease.

TL;DR: It is proposed that an infectious organism, a viable external agent, is the initiating or persistent cause of RA, and that this agent directly and indirectly results in the phenomena of immune complex disease, hypersensitivity, and autoimmunity.

TL;DR: Osteoarthritis is a common ailment that afflicts a major portion of the authors' older generation, producing a great deal of pain and suffering, and with the great advances in all fields of medicine, patients are living longer and can successfully undergo most surgical procedures.