The platinum group elements are significant compounds used in numerous fields of human life. Besides of often discussed toxic effect the platinum compounds show the therapeutic effects. Nowadays, platinum-based cytostatic are still the most frequently used drugs in oncology. Due to their proved medicinal purposes the behavior in the organism should to be intensively studied as well as their interactions with DNA and other important biological molecules. This review summarizes the recent results in the platinum drug field and discusses the behavior of platinum compounds in cells. The interaction of platinum and DNA with respect to the change of the DNA structure are also clarified.

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5th International Conference "Platinum Metals in the Modern Industry, Hydrogen Energy and Life Maintenance of the Future"

Mechanisms of Uptake and Interaction of Platinum Based Drugs in Eukaryotic Cells

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5th International Conference "Platinum Metals in the Modern Industry, Hydrogen Energy and Life Maintenance of the Future"

Citations

Mechanisms of Uptake and Interaction of Platinum Based Drugs in Eukaryotic Cells

References

Mechanisms of Uptake and Interaction of Platinum Based Drugs in Eukaryotic Cells

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