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A study of the adrenotropic receptors

Raymond P. Ahlquist
- pp 207-224
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The article was published on 2017-01-01 and is currently open access. It has received 2470 citations till now.

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Journal ArticleDOI

Differentiation of receptor systems activated by sympathomimetic amines.

TL;DR: The classification of receptor systems which are activated by sympathomimetic amines has engaged the attention of many investigators as mentioned in this paper, who have suggested the convenient designations of alpha (α) and beta (β) to distinguish major differences in the responses elicited in various organ systems.
Journal ArticleDOI

The beta adrenergic theory of the atopic abnormality in bronchial asthma

TL;DR: An alternative to the classical concept of immunological concepts, which came to be known as the bet, a adrenergic concept, is based on model experiments and other considerations, and cannot easily account for some of the significant facts surrounding this disease.
Book ChapterDOI

The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory

TL;DR: A wide variety of tissues undergo a change of functional state on exposure to noradrenaline or adrenaline, and agents which produce responses in tissues by interacting with adrenoceptors are referred to, for convenience, as adrenergic agonists.
Journal ArticleDOI

A functional basis for classification of alpha-adrenergic receptors.

TL;DR: A division of adrenergic receptors into alpha and beta types could conceivably lead to the development of powerful agents even more selective for inhibition of renin release, control of blood pressure by a central site of action, reduction of fever, and possible other scientific or therapeutic applications.