Accelerated extraction of Xanthone from Mangosteen pericarp using ultrasonic technique
TLDR
Ultrasound assisted extraction (UAE) was employed to extract xanthone from dried M. pericarp and compared with soxhlet extraction and maceration and the optimum conditions from Box-Behnken design were determined to be temperature 33°C, amplitude 75 and 80% ethanol.Abstract:
Mangosteen pericarp has been used for long time as traditional medicine. One of main active ingredient in M. pericarp is xanthone. Xanthone has remarkable effects on cardiovascular health, antiviral and anti-inflammatory. Ultrasonic Assisted Extraction (UAE) was employed to extract xanthone from dried M. pericarp and compared with soxhlet extraction and maceration. The UAE was applied by various temperature (33, 45 and 55°C), amplitude (25, 50 and 75%) and solvent (0, 50 and 95% ethanol) for 1 h extraction time. The conditions for the highest xanthone recovery were determined at temperature 33°C, and 50% ethanol at 50% amplitude, resulting 0.16 mg/g of dried M. pericarp. The Box-Behnken design was applied to investigate the optimum condition of UAE. The optimum conditions from Box-Behnken design to obtain the highest xanthone recovery were determined to be temperature 33°C, amplitude 75 and 80% ethanol. The results presented that for UAE in 0.5 h, soxhlet extraction in 2 h and maceration in 2 h, the extracted xanthones were 0.1760, 0.1221 and 0.0565 mg/g of dried M. pericarp respectively.
Key word: Ultrasound assisted extraction (UAE), Mangosteen pericarp, xanthone, maceration.read more
Citations
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Journal ArticleDOI
Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction.
Nor Azizah Mohammad,Dayang Norulfairuz Abang Zaidel,Ida Idayu Muhamad,Mariani Abdul Hamid,Harisun Yaakob,Yanti Maslina Mohd Jusoh +5 more
TL;DR: MAE led to a slightly similar antioxidant capacity and a higher extraction of α-mangostin, a major xanthone of mangosteen pericarp as compared to water bath-maceration technique, and confirmed that the examined model was acceptable and relevant.
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In Vitro Permeation and Skin Retention of α-Mangostin Proniosome.
TL;DR: The results suggested that proniosomes can be utilized as a carrier for highly lipophilic compound like α-mangostin for topical application.
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Optimization of the antioxidant capacity of mangosteen peels (Garcinia mangostana L.) extracts: Management of the drying extraction processes
Mónica Leon García,María Hernández Carrión,Sebastián Escobar,Aureliano Rodríguez,Jader Rodríguez Cortina +4 more
TL;DR: Results showed that the best operating conditions to maximize the antioxidant capacity of mangosteen peels were a drying temperature of 70℃ and using high-power ultrasound as extraction method.
Dissertation
Development of a xanthone-enriched honeybush tea extract
TL;DR: In this article, the authors present a collection of tables and lists of figures from literature review and literature review, including a discussion of the relationship between figures and tables, as well as a list of acknowledgements.
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Separation of xanthone and vitamin E from Calophyllum inophyllum leaf
Hakun Wirawasista Aparamarta,Safrina Hapsari,Reinaldi Ismawan,Violita Anggraeni,Arief Widjaja,Tri Widjaja,Yi-Hsu Ju,Setiyo Gunawan +7 more
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