Journal ArticleDOI
Acute pancreatitis: value of CT in establishing prognosis.
Reads0
Chats0
TLDR
A CT severity index, based on a combination of peripancreatic inflammation, phlegmon, and degree of pancreatic necrosis as seen at initial CT study, was developed and showed clear trends in patients who initially had or developed more than 30% necrosis.Abstract:
The presence and degree of pancreatic necrosis (30%, 50%, or greater than 50%) was evaluated by means of bolus injection of contrast material and dynamic sequential computed tomography (CT) in 88 patients with acute pancreatitis at initial and follow-up examinations. Pancreatic necrosis was defined as lack of enhancement of all or a portion of the gland. Length of hospitalization, morbidity, and mortality in patients with early or late necrosis (22 patients) were evaluated and compared with the same criteria in the rest of the group. Patients with necrosis had a 23% mortality and an 82% complication rate; patients without necrosis had 0% mortality and 6% morbidity. When only the initial assessment was considered, patients with peripancreatic phlegmons and necrosis had 80% morbidity, compared with 36% morbidity in those with phlegmons and no necrosis. Serious complications occurred in patients who initially had or developed more than 30% necrosis. A CT severity index, based on a combination of peripancreatic inflammation, phlegmon, and degree of pancreatic necrosis as seen at initial CT study, was developed. Patients with a high CT severity index had 92% morbidity and 17% mortality; patients with a low CT severity index had 2% morbidity, and none died.read more
Citations
More filters
Journal ArticleDOI
Evolution of nutritional support in acute pancreatitis.
TL;DR: The evidence in favour of initiating nutritional support in patients with severe acute pancreatitis and the effects of such support on the course of the disease are examined.
Journal ArticleDOI
Splenic and perisplenic involvement in acute pancreatitis: determination of prevalence and morphologic helical CT features.
TL;DR: Splenic vein thrombosis and splenic infarction are relatively common CT findings in association with acute pancreatitis and the CTSI proves to be accurate in predicting these complications as there is a statistically significant correlation between the prevalence of these complications and the severity of pancreatitis.
Journal ArticleDOI
Comparison of clinical course and outcome of acute pancreatitis according to the two main etiologies: alcohol and gallstone
TL;DR: More severe forms of AP and local complication, such as pseudocyst formation, are associated with alcoholic AP compared with biliary AP.
Journal ArticleDOI
Safety and efficacy of vitamin-based antioxidant therapy in patients with severe acute pancreatitis: a randomized controlled trial.
Dipika Bansal,Ashish Bhalla,Deepak K. Bhasin,Promila Pandhi,Navneet Sharma,Surinder Singh Rana,Samir Malhotra +6 more
TL;DR: It is demonstrated that there is no significant benefit from antioxidant therapy in patients with established severe acute pancreatitis, and univariate analysis showed marginal benefit with antioxidant treatment.
Journal ArticleDOI
Factors and outcomes associated with pancreatic duct disruption in patients with acute necrotizing pancreatitis.
Ji Woong Jang,Myung-Hwan Kim,Dongwook Oh,Dong Hui Cho,Tae Jun Song,Do Hyun Park,Sang Soo Lee,Dong Wan Seo,Sung Koo Lee,Sung-Hoon Moon +9 more
TL;DR: Extensive necrosis, enlarging/refractory pancreatic fluid collections, persistence of amylase-rich output from percutaneous drainage, and amyl enzyme-rich ascites/pleural effusion were more frequently associated with MPD disruption, which is not uncommon in patients with ANP with clinical suspicion on ductal disruption.
Related Papers (5)
A Clinically Based Classification System for Acute Pancreatitis: Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 Through 13, 1992
Practice guidelines in acute pancreatitis.
Peter A. Banks,Martin L. Freeman,Ronnie Fass,Darren Baroni,Ece Mutlu,David E. Bernstein,Henry P. Parkman,Adil E. Bharucha,Charlene M. Prather,William R. Brugge,Daniel S. Pratt,Lin Chang,Albert Roach,William Y. Chey,Richard E. Sampliner,Matthew E. Cohen,Subbaramiah Sridhar,John T. Cunningham,Nimish Vakil,Steven A. Edmundowicz,Miguel A. Valdovinos,John M. Inadomi,Benjamin C.Y. Wong,Timothy R. Koch,Alvin M. Zfass +24 more