Journal ArticleDOI
Analysis of Poisson data in crossover experimental designs.
M. W. J. Layard,J. N. Arvesen +1 more
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This article is published in Biometrics.The article was published on 1978-09-01. It has received 35 citations till now. The article focuses on the topics: Crossover & Poisson distribution.read more
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Crossover and Self-Controlled Designs in Clinical Research
TL;DR: This work investigated the use of the crossover design in 13 crossover studies that appeared in the Journal during 1978 and 1979 and reported briefly on 28 additional studies of a single treatment each, in which each patient served as his or her own control before or after treatment or both.
Journal ArticleDOI
On the evaluation of the clinical effects of acupuncture
George Lewith,David Machin +1 more
TL;DR: It is suggested that meaningful comparisons between alternative treatments may be made by using ‘pain free intervals’ with subsequent analysis using life table techniques, as well as the statistical methodology necessary in the design of acupuncture trials.
Journal ArticleDOI
Some Views on Parametric and Non-Parametric Analysis for Repeated Measurements and Selected Bibliography
TL;DR: In this paper, a review of statistical strategies for the analysis of data from split-plot experiments and repeated measurements experiments is presented. And a selected bibliography of references for these and related methods is given.
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Repeated measurements designs. A review
TL;DR: In this article, the impact of optimal design theory on the design of repeated measurements experiments is discussed, and some construction methods for these designs are presented. And a bibliography of these designs is provided at the end of this paper.
Journal ArticleDOI
Designing clinical trials for paroxysmal atrial tachycardia and other paroxysmal arrhythmias.
TL;DR: Treatment of paroxysmal atrial tachycardia can be studied efficiently using a clinical trial with a two period cross-over design in which placebo and investigational therapy are delivered in random order.