Bladder smooth muscle dysfunction in patients with irritable bowel syndrome
TLDR
This is the first study to provide objective evidence that patients with irritable bowel syndrome may have a disorder of smooth muscle or its innervation that is not confined to the gastrointestinal system.Abstract:
Urodynamic studies were carried out on 30 patients with irritable bowel syndrome and 30 matched controls. Fifty per cent of the irritable bowel patients compared with only 13% of the control group had evidence of bladder dysfunction (p = 0.006). In the irritable bowel group detrusor instability was observed in 10 patients compared with only one control subject (p = 0.008). A steep cystometrogram occurred in five irritable bowel patients and three controls (NS). Detrusor instability was most common in patients with a bowel habit characterised by alternating constipation and diarrhoea. This is the first study to provide objective evidence that patients with irritable bowel syndrome may have a disorder of smooth muscle or its innervation that is not confined to the gastrointestinal system.read more
Citations
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Irritable bowel syndrome in the general population.
Roger Jones,S. Lydeard +1 more
TL;DR: Symptoms consistent with a diagnosis of irritable bowel syndrome are present in almost one quarter of the general population and tend to be associated with a number of other complaints and conditions, some of which may reflect smooth muscle dysfunction.
Journal ArticleDOI
Irritable bowel-type symptoms in HMO examinees. Prevalence, demographics, and clinical correlates.
TL;DR: In this article, a study of irritable bowel-type symptoms in 1264 health examinees using a self-administered questionnaire and psychological tests revealed they are common throughout adulthood.
Journal ArticleDOI
Physiology and pathophysiology of colonic motor activity (2).
TL;DR: The basic motor function of the colon is to mix and knead its contents, propel them slowly in the caudad direction, hold them in the distal colon until defecation, and provide a strong propulsive force duringdefecation.
Journal ArticleDOI
Dysmotility of the small intestine in irritable bowel syndrome.
TL;DR: Several stimuli were applied in an attempt to unmask intestinal dysmotility in patients with IBS, finding that patients with diarrhoea were more sensitive to stimuli than those with constipation.
References
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Bowel patterns among subjects not seeking health care. Use of a questionnaire to identify a population with bowel dysfunction.
TL;DR: In this article, the authors devised a brief selfadministered questionnaire which, when used among a group of 789 students and hospital employees, disclosed that 94.2% had stool frequencies between three per day and three per week, and that 17.1% had bowel dysfunction.
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Functional Bowel Disorders in Apparently Healthy People
TL;DR: Four clinically distinct functional bowel syndromes existed in almost one-third of the subjects studied, and constipation seemed to increase with age.
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Non-colonic features of irritable bowel syndrome.
TL;DR: A wide variety of non-gastrointestinal symptoms were significantly more common than in a group of 100 age, sex, and social class matched controls and may be indicative of a much more diffuse disorder of smooth muscle than has previously been appreciated.