Journal ArticleDOI
Caries inhibition in the rat by water-borne and enamel-bound fluoride.
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Osborne-Mendel rats 22–25 days of age were subjected to a 7-day precaries test period during which they were fed a high starch diet and drank distilled water containing no added fluoride or with 10, 5 times the recommended concentration of fluoride.Abstract:
Osborne-Mendel rats 22–25 days of age were subjected to a 7-day precaries test period during which they were fed a high starch diet and drank distilled water containing no added fluoride or with 10, 5read more
Citations
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Journal ArticleDOI
Mechanistic Aspects of the Interactions Between Fluoride and Dental Enamel
TL;DR: This article critically reviews the current information about tooth-fluoride interactions, both from laboratory and clinical studies, and finds that the physiological balance between hard tissue breakdown and repair is favorably shifted by fluoride.
Journal ArticleDOI
Rational use of fluorides in caries prevention. A concept based on possible cariostatic mechanisms.
TL;DR: It is concluded that the major cariostatic effect of water fluoridation, fluoride tooth paste and mouth rinses can probably be ascribed to regular increases in fluoride ion activity in the oral fluids.
Journal ArticleDOI
In vitro studies on the effects of fluoride on de- and remineralization.
TL;DR: For the in vivo patterns and the effects of caries-preventive substances to be studied, de- and remineralization can best be examined with a pH-cycling system in which the pH depressions occurring in the oral environment are mimicked in a laboratory model.
Journal ArticleDOI
Effect of Low Levels of Fluoride in Solution on Enamel Demineralization in vitro
TL;DR: The results obtained were found to be consistent with a proposed hypothesis that the net rate of enamel Demineralization will be reduced in a demineralizing medium supersaturated with respect to less soluble fluoridated phases, due to the enhancement of the precipitation rate offluoridated apatitic phases relative to the rate of dissolution of the original enamel surface.
Journal ArticleDOI
Physicochemical Perspectives on the Cariostatic Mechanisms of Systemic and Topical Fluorides
Henry C. Margolis,E.C. Moreno +1 more
TL;DR: It is concluded that the benefits provided by water fluoridation result, to a large degree, from a topical effect and it is suggested that clinical procedures be developed to establish and maintain low levels of free fluoride in plaque fluid.
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