Open AccessJournal Article
Correction of congenital diaphragmatic hernia in utero. II. Simulated correction permits fetal lung growth with survival at birth.
TLDR
Efficacy of in utero correction was confirmed by three twin studies in which simulated CDH in one twin was compared with simulated correction in the other and a significant increase in lung weight, air capacity, compliance, and area of the pulmonary vascular bed was produced.About:
This article is published in Surgery.The article was published on 1980-08-01 and is currently open access. It has received 218 citations till now. The article focuses on the topics: Congenital diaphragmatic hernia & Lung.read more
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A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic hernia.
Michael R. Harrison,Roberta L. Keller,Samuel Hawgood,Joseph A. Kitterman,Per L. Sandberg,Diana L. Farmer,Hanmin Lee,Roy A. Filly,Jody A. Farrell,Craig T. Albanese +9 more
TL;DR: Tracheal occlusion did not improve survival or morbidity rates in this cohort of fetuses with congenital diaphragmatic hernia and was inversely related to survival in both groups.
Journal ArticleDOI
Correction of congenital diaphragmatic hernia in utero: VI. hard-earned lessons
Michael R. Harrison,N. Scott Adzick,Alan W. Flake,Russell W. Jennings,James M. Estes,Thomas E. MacGillivray,Jane T. Chueh,James D. Goldberg,Roy A. Filly,Ruth B. Goldstein,Mark A. Rosen,Charles Cauldwell,Anne H Levine,Lori J. Howell +13 more
TL;DR: It is reported that repair of CDH in utero is physiologically sound and safe for the mother, but technically difficult especially when the liver is herniated into the fetal chest.
Journal ArticleDOI
Diaphragmatic hernia in the fetus: Prenatal diagnosis and outcome in 94 cases***
N. Scott Adzick,Michael R. Harrison,Philip L. Glick,Donald K. Nakayama,Frank A. Manning,Alfred A. deLorimier +5 more
TL;DR: Surgical intervention before birth may be necessary to improve survival of the fetus with CDH and polyhydramnios and current techniques can detect lethal nonpulmonary anomalies and prevent diagnostic errors.
Journal ArticleDOI
Experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia in congenital diaphragmatic hernia
John W. DiFiore,Dario O. Fauza,Richard Slavin,Craig A. Peters,James C. Fackler,Jay M. Wilson +5 more
TL;DR: Experimental fetal DH produces hypoplastic lungs that are not capable of adequate gas exchange with conventional ventilation and are associated with a normal maturation pattern based on histological appearance, normal airspace fraction, and normal alveolar numerical density.
Journal ArticleDOI
Fetal surgery for congenital hydronephrosis.
Michael R. Harrison,M S Golbus,R A Filly,Peter W. Callen,Michael Katz,A.A. de Lorimier,Mark A. Rosen,A R Jonsen +7 more
TL;DR: In the fetus with severe bilateral hydronephrosis secondary to urethral oesophageal encephalopathy, the placenta may be severely damaged during pregnancy and the baby may not have a chance of survival.