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James D. Goldberg

Researcher at University of California, San Francisco

Publications -  67
Citations -  3973

James D. Goldberg is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Prenatal diagnosis & Pregnancy. The author has an hindex of 30, co-authored 66 publications receiving 3634 citations. Previous affiliations of James D. Goldberg include Icahn School of Medicine at Mount Sinai & University of Minnesota.

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Correction of congenital diaphragmatic hernia in utero: VI. hard-earned lessons

TL;DR: It is reported that repair of CDH in utero is physiologically sound and safe for the mother, but technically difficult especially when the liver is herniated into the fetal chest.
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Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies

TL;DR: A small number of cases of occult malignancy were subsequently diagnosed among pregnant women whose noninvasive prenatal testing results showed discordance with the fetal karyotype, and the clinical importance of these findings will require further research.
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Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis.

TL;DR: A thickened nuchal fold in the second trimester may be useful in distinguishing unaffected fetuses from those with Down syndrome, but the overall sensitivity of this finding is too low for it to be a practical screening test for Down syndrome.
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Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in maternal blood.

TL;DR: In two pregnancies at risk for sickle cell anaemia and β–thalassaemia, the fetal genotypes are successfully identified and prenatal diagnosis of single gene disorders by recovering fetal cells from maternal circulation appears to be a feasible approach.
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Correction of congenital diaphragmatic hernia in utero VIII: Response of the hypoplastic lung to tracheal occlusion.

TL;DR: Investigating the pathophysiology of CDH and its repair in fetal lambs found that obstructing the normal egress of fetal lung fluid enlarges developing fetal lungs, reduces the herniated viscera, and accelerates lung growth, resulting in improved pulmonary function after birth.