Cronkhite- Canada syndrome; a case report and review of the literature.
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TLDR
A 50 year-old man with hamartomatous polyps throughout the colon and long-lasting diarrhea not responding to typical therapies during three years is presented.Abstract:
Cronkhite- Canada syndrome (CCS) considered as a rare and non-hereditary disorder. Gastrointestinal polyposis and diarrhea along with some extra signs and symptoms such as hypoproteinemia, and epidermal manifestations are recognized in this syndrome. The pathophysiology of this syndrome is not completely understood and it seems that inflammatory processes may be involved. We present a 50 year-old man with hamartomatous polyps throughout the colon and long-lasting diarrhea not responding to typical therapies during three years.read more
Citations
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Cronkhite–Canada syndrome six decades on: the many faces of an enigmatic disease
TL;DR: Close correlation with clinical findings, including any pertinent ectodermal abnormalities, and careful examination of biopsies derived from polypoid and endoscopically spared mucosa will ensure a timely and correct diagnosis in patients with this enigmatic syndrome.
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Steroid-resistant Cronkhite-Canada syndrome successfully treated by cyclosporine and azathioprine.
Naoki Ohmiya,Masanao Nakamura,Takeshi Yamamura,Koji Yamada,Asuka Nagura,Toru Yoshimura,Yoshiki Hirooka,Takayuki Matsumoto,Ichiro Hirata,Hidemi Goto +9 more
TL;DR: The angiotensin II type 2 receptor and the gastrointestinal tract, and the role for preand postjunctional AT(1A) receptors.
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Cronkhite-Canada syndrome polyps infiltrated with IgG4-positive plasma cells
TL;DR: Both histologic findings and treatment response to steroid suggested an autoimmune mechanism underling CCS.
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Cronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhoea in a Young Man.
Dhrubajyoti Bandyopadhyay,Adrija Hajra,Vijayan Ganesan,Suvrendu Sankar Kar,Debarati Bhar,Manas Layek,Sabyasachi Mukhopadhyay,Cankatika Choudhury,Vivek Choudhary,Prasun Banerjee +9 more
TL;DR: Close correlation with clinical findings, including pertinent ectodermal abnormalities, endoscopic studies, and careful examination of biopsies will ensure a timely and correct diagnosis of CCS.
References
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Generalized gastrointestinal polyposis; an unusual syndrome of polyposis, pigmentation, alopecia and onychotrophia.
TL;DR: Two cases are reported below in which the presenting complaints were disturbances in gastrointestinal function, pigmentation of the skin, alopecia and atrophy of the fingernails and toenails.
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The Cronkhite-Canada Syndrome. An analysis of clinical and pathologic features and therapy in 55 patients.
Erno S. Daniel,Shelly L. Ludwig,Klaus J. Lewin,Ruth M. Ruprecht,George M. Rajacich,Arthur D. Schwabe +5 more
Journal ArticleDOI
Natural history of colorectal cancer.
TL;DR: A better understanding of various high-risk groups and the application of screening methods to these individuals and to people at average risk is learned, which may provide new opportunities for control of colorectal cancer through secondary prevention.
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Review article: the non-inherited gastrointestinal polyposis syndromes.
Eric M. Ward,Herbert C. Wolfsen +1 more
TL;DR: A review of the clinical and histo‐ pathological aspects of the non‐inherited gastrointestinal polyposis syndromes to include the Cronkhite–Canada syndrome, hyperplastic polyPOSis and lipomatouspolyposis is presented.
Journal Article
Cronkhite-Canada syndrome: epidemiological study of 110 cases reported in Japan.
TL;DR: Mental and physical stress have been confirmed as among the most important risk factors for this syndrome and Hypogeusia is the dominant initial symptom which usually is followed by diarrhea and ectodermal changes including alopecia, nail dystrophy and skin pigmentation.