Fig 4. SeqUnwinder analysis of sequence features at multi-condition TF binding sites for ENCODE YY1 datasets. (A) Heatmaps showing the YY1 ChIP-seq reads at curated YY1 binding sites, stratified based on binding across cell-lines and distance from annotated mRNA TSS. The order of subclasses is: Shared and Proximal, Shared and Distal, K562 and Proximal, K562 and Distal, GM12878 and Proximal, GM12878 and Distal, H1-hESC and Proximal, and H1-hESC and Distal. (B) De novo motifs and corresponding label-specific scores identified using SeqUnwinder at events defined in A). For consistency across figures, we fix the color saturation values to -0.4 and 0.4.
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