Journal ArticleDOI
Diabetes and Cardiovascular Disease During Androgen Deprivation Therapy for Prostate Cancer
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This article is published in Yearbook of Urology.The article was published on 2007-01-01. It has received 334 citations till now. The article focuses on the topics: Androgen deprivation therapy & Prostate cancer.read more
Citations
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Journal ArticleDOI
Radiotherapy and Short-Term Androgen Deprivation for Localized Prostate Cancer
Christopher U. Jones,Daniel P. Hunt,David G. McGowan,Mahul B. Amin,Michael Chetner,Deborah Watkins Bruner,Mark H. Leibenhaut,Siraj Husain,Marvin Rotman,Luis Souhami,Howard M. Sandler,William U. Shipley +11 more
TL;DR: Among patients with stage T1b, T1c, T2a, or T2b prostate adenocarcinoma and a PSA level of 20 ng per milliliter or less, the use of short-term ADT for 4 months before and during radiotherapy was associated with significantly decreased disease-specific mortality and increased overall survival.
Journal ArticleDOI
Adverse Effects of Androgen Deprivation Therapy and Strategies to Mitigate Them
Paul L. Nguyen,Shabbir M.H. Alibhai,Shehzad Basaria,Anthony V. D'Amico,Philip W. Kantoff,Nancy L. Keating,David F. Penson,Derek J. Rosario,Bertrand Tombal,Matthew R. Smith +9 more
TL;DR: ADT is often a necessary component of the treatment of aggressive prostate cancer, yet it has known harms that can impair health and quality of life.
Journal ArticleDOI
Combined Resistance and Aerobic Exercise Program Reverses Muscle Loss in Men Undergoing Androgen Suppression Therapy for Prostate Cancer Without Bone Metastases: A Randomized Controlled Trial
TL;DR: A relatively brief exposure to exercise significantly improved muscle mass, strength, physical function, and balance in hypogonadal men compared with normal care and could be recommended for patients undergoing AST as an effective countermeasure to these common treatment-related adverse effects.
Journal ArticleDOI
Diabetes and Cardiovascular Disease During Androgen Deprivation Therapy: Observational Study of Veterans With Prostate Cancer
TL;DR: Androgen deprivation therapy with GnRH agonists was associated with an increased risk of diabetes and cardiovascular disease and oral antiandrogen monotherapy was not associated with any outcome studied.
Journal ArticleDOI
Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality
TL;DR: Among patients 65 years or older treated with external beam radiation therapy, brachytherapy, or cryotherapy, ADT use was associated with a higher cumulative incidence of death from cardiovascular causes, but the difference did not reach statistical significance.
References
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Journal ArticleDOI
Radiotherapy and Short-Term Androgen Deprivation for Localized Prostate Cancer
Christopher U. Jones,Daniel P. Hunt,David G. McGowan,Mahul B. Amin,Michael Chetner,Deborah Watkins Bruner,Mark H. Leibenhaut,Siraj Husain,Marvin Rotman,Luis Souhami,Howard M. Sandler,William U. Shipley +11 more
TL;DR: Among patients with stage T1b, T1c, T2a, or T2b prostate adenocarcinoma and a PSA level of 20 ng per milliliter or less, the use of short-term ADT for 4 months before and during radiotherapy was associated with significantly decreased disease-specific mortality and increased overall survival.
Journal ArticleDOI
Adverse Effects of Androgen Deprivation Therapy and Strategies to Mitigate Them
Paul L. Nguyen,Shabbir M.H. Alibhai,Shehzad Basaria,Anthony V. D'Amico,Philip W. Kantoff,Nancy L. Keating,David F. Penson,Derek J. Rosario,Bertrand Tombal,Matthew R. Smith +9 more
TL;DR: ADT is often a necessary component of the treatment of aggressive prostate cancer, yet it has known harms that can impair health and quality of life.
Journal ArticleDOI
Combined Resistance and Aerobic Exercise Program Reverses Muscle Loss in Men Undergoing Androgen Suppression Therapy for Prostate Cancer Without Bone Metastases: A Randomized Controlled Trial
TL;DR: A relatively brief exposure to exercise significantly improved muscle mass, strength, physical function, and balance in hypogonadal men compared with normal care and could be recommended for patients undergoing AST as an effective countermeasure to these common treatment-related adverse effects.
Journal ArticleDOI
Diabetes and Cardiovascular Disease During Androgen Deprivation Therapy: Observational Study of Veterans With Prostate Cancer
TL;DR: Androgen deprivation therapy with GnRH agonists was associated with an increased risk of diabetes and cardiovascular disease and oral antiandrogen monotherapy was not associated with any outcome studied.
Journal ArticleDOI
Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality
TL;DR: Among patients 65 years or older treated with external beam radiation therapy, brachytherapy, or cryotherapy, ADT use was associated with a higher cumulative incidence of death from cardiovascular causes, but the difference did not reach statistical significance.