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Open AccessJournal ArticleDOI

Differential expression of interleukin-6 in leprosy reactions.

Mukul Sharma, +1 more
- 28 Aug 2021 - 
- pp 1-2
About: 
This article is published in Indian Journal of Dermatology, Venereology and Leprology.The article was published on 2021-08-28 and is currently open access. It has received 0 citations till now. The article focuses on the topics: Interleukin 6.

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References
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Journal ArticleDOI

The Continuing Challenges of Leprosy

David M. Scollard, +5 more
- 01 Apr 2006 - 
TL;DR: This review focuses on recent advances in the understanding of M. leprae and the host response to it, especially concerning molecular identification of M.'s genome, transcriptome, and proteome, its mechanisms of microbial resistance, and recognition of strains by variable-number tandem repeat analysis.
Journal ArticleDOI

Interleukin-6: a potent biomarker of mycobacterial infection

Prati Pal Singh, +1 more
- 21 Dec 2013 - 
TL;DR: IL-6 appears to be the only major cytokine elaborated by mycobacteria-infected PMs, in vitro, and thus may function as a potent biomarker of myc Cobacterial infection, either stand-alone or along with other cytokines.
Journal ArticleDOI

Leprosy Reactions Show Increased Th17 Cell Activity and Reduced FOXP3+ Tregs with Concomitant Decrease in TGF-β and Increase in IL-6.

Chaman Saini, +3 more
- 01 Apr 2016 - 
TL;DR: The combined effect of reduced TGF-β and enhanced IL-6, IL-21 cytokines influence the balance between Th17 or Treg cells in leprosy reactions as reported in the murine models and autoimmune diseases.
Journal ArticleDOI

Genetic and Immunological Evidence Implicates Interleukin 6 as a Susceptibility Gene for Leprosy Type 2 Reaction

Ana Lúcia O.M. Sousa, +6 more
- 01 May 2012 - 
TL;DR: Two nested case-control studies were built from a cohort of 409 patients with leprosy from central Brazil, monitored for T1R and T2R, and evidence for association between T 2R and IL-6 tag single-nucleotide polymorphisms was found.
Journal ArticleDOI

Increased serum levels of interleukin-6 in erythema nodosum leprosum suggest its use as a biomarker.

Fátima Regina Vilani-Moreno, +7 more
- 23 Mar 2021 - 
TL;DR: In this paper, the authors evaluated selected serum mediators involved in the innate and adaptive immune responses to identify possible immunomarkers for Erythema nodosum leprosum (ENL).