Journal ArticleDOI
Early to Bed or Sleep Revisited
TLDR
For many years, sleep was regarded as a passive process during which bodily functions slowed or stopped to allow reparative processes to operate, but the first inklings of a different theory were noted by sleep physiologists who described distinct changes in the electrical activity of the brain during sleep.Abstract:
For many years, sleep was regarded as a passive process during which bodily functions slowed or stopped to allow reparative processes to operate. The first inklings of a different theory were noted by sleep physiologists who described distinct changes in the electrical activity of the brain during sleep. 1 On the basis of electroencephalographic and eye movement recordings, sleep can be divided into alternating periods of rapid eye movement (REM) sleep that is associated with dreaming, and non-REM, or slow-wave sleep, which is divided into stages 1 through 4 according to specific EEG patterns and is not associated with dreaming. This alternating pattern of REM and non-REM sleep comprises a sleep cycle, several of which occur during each night's sleep. It was also discovered that an infant's sleep cycle is different from an older child's cycle and from an adult's sleep cycle. The length of each cycle, the amount ofread more
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Neonatal Dystrophia Myotonica: Electrophysiologic Studies
TL;DR: The diagnosis of dystrophia myotonica was established in a boy 3 hours old, and confirmed by family study and electromyography (EMG) at 5 days, and clinical features included hypotonia, facial diparesis, "tented" upper lip, and arthrogryposis of both knees.
Journal ArticleDOI
Hypothalamic Releasing Substances and Inhibitors
TL;DR: Integration of the hypothalamus into the endocrine system has opened the door to the uncovering of the links between neural activity, such as rage, emotion, and sleep, and their effects on endocrine function.
References
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Journal ArticleDOI
Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming.
TL;DR: Records from a large number of nights in single individuals indicated that some could maintain a very striking regularity in their sleep pattern from night to night, and that body movement, after rising to a peak, dropped sharply at the onset of rapid eye movements and rebounded abruptly as the eye movements ceased.
Journal ArticleDOI
Age-related change in the twenty-four-hour spontaneous secretion of growth hormone.
TL;DR: Growth hormone was secreted during both awake and asleep periods but the number of secretory episodes was less than in adole...
Journal ArticleDOI
Synchronization of Augmented Luteinizing Hormone Secretion with Sleep during Puberty
Robert M. Boyar,Jordan W. Finkelstein,Howard P. Roffwarg,Sheldon Kapen,Elliot D. Weitzman,Leon Hellman +5 more
TL;DR: In all pubertal subjects, an increase in LH secretion was associated with sleep that resulted in significantly higher mean LH concentrations than with the subject awake, providing a biologic index for the identification of sexual maturation stages.
Journal ArticleDOI
Cortisol Is Secreted Episodically by Normal Man
Leon Hellman,Fujinori Nakada,Joseph Curti,Elliot D. Weitzman,Jacob Kream,Howard P. Roffwarg,Steven Ellman,David K. Fukushima,T. F. Gallagher +8 more
TL;DR: It was shown that in the early morning hours during sleep cortisol was secreted in episodic bursts which were separated by intervals during which there was no cortisol sec...
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Sleep and its disorders in infants and children: a review.
Thomas F. Anders,Pearl Weinstein +1 more
TL;DR: The normal developmental course of the "active" and the "quiet" sleep states from birth through childhood is described, and within the context of these recent electro-physiologic findings, the abnormalities of sleep state organization during the neonatal period, the physiologic disorders of sleep in older children, and the psychological disturbances manifested through sleep are reviewed.