Gram-negative septicemia: a growing threat.
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This article is published in Annals of Surgery.The article was published on 1967-10-01 and is currently open access. It has received 131 citations till now.read more
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Gram-negative bacteremia: IV. Re-evaluation of clinical features and treatment in 612 patients
TL;DR: Age, underlying host disease, granulocytopenia, congestive heart failure, diabetes mellitus, renal insufficiency, nosocomial infections, and antecedent treatment with antibiotics, corticosteroids, and antimetabolites significantly increased fatality rates.
Journal ArticleDOI
Infections Caused by Pseudomonas aeruginosa
TL;DR: Many new drugs with antipseudomonal activity, including penicillins, cephalosporins, and other beta-lactams, have been introduced in recent years and offer the potential for new approaches to therapy for these infections.
Journal ArticleDOI
Multiple-Organ-Failure Syndrome
TL;DR: The panelists for the discussion were C. James Carrico, MD, from Seattle; Jonathan Meakins, DSc, FRCSC, FACS, from Montreal; Donald Fry,MD, from Cleveland; and Ronald V. Maier, MD from Seattle, who all had experience of multiple-organ-failure syndrome.
Journal ArticleDOI
Gram-negative bacteremia. III. Reassessment of etiology, epidemiology and ecology in 612 patients.
TL;DR: It is indicated that bacterial factors, other than antibiotic resistance, have little influence on the outcome of gram-negative bacteremia and that gram- negative bacilli function primarily as "opportunistic" pathogens.
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The grading of sepsis.
E A Elebute,H B Stoner +1 more
TL;DR: A simple system for grading the severity of sepsis has been developed by scoring the attributes of septicaemia under four headings: local effects of infection, pyrexia, secondary effects of Sepsis and laboratory data.
References
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Occurrence of serious bacterial infections since introduction of antibacterial agents
TL;DR: The introduction and widespread use of chemotherapeutic and antibiotic agents has resulted in profound changes in the number and character of infections that are being encountered, particularly those occurring within hospitals.
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Septicemia of the newborn.
TL;DR: Fever, abdominal distention, icterus, and hepatomegaly were the most common clinical manifestations suggesting sepsis, however, in most patients the clinical picture was one of general, rather vague, systemic illness.
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Bacteremia owing to gram-negative bacilli: experiences in the treatment of 137 patients in a 15-year period
TL;DR: The evolution of effective antibiotic therapy has greatly altered the outlook of many infectious states, one of which is the invasion of the blood stream by microorganisms.
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The Pathogenesis and Management of Shock Due to Infection
TL;DR: During the initial stages of shock due to infection the patients are alert and exhibit fever, chills, pallor, tachycardia, hyperpnea, and a moist skin.