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Journal ArticleDOI

HEPATITIS AND ITS SEQUELAE, INCLUDING THE DEVELOPMENT OF PORTAL CIRRHOSIS: Observations on One Hundred Cases

M F Koszalka, +1 more
- 01 Nov 1949 - 
- Vol. 84, Iss: 5, pp 782-797
TLDR
Observations are presented to bring out the following points: that the virulence of the organism during the two years previous to this report has been great, especially when it has been transmitted by the infusion of plasma or blood.
Abstract
THE PROBLEM of hepatitis has become a very real one since the onset of World War II. Just as in and after World War I, the incidence of hepatitis and perhaps the virulence of the icterogenic substance, which has definitely been shown to be a virus, have become greater. Our observations are presented to bring out the following points: That the virulence of the organism during the two years previous to this report has been great, especially when it has been transmitted by the infusion of plasma or blood. That there is a correlation between the results of liver function tests and the clinical course of the disease. That the physician should be alert concerning the possibility of homologous serum jaundice and of syringe-transmitted hepatitis. That chronic hepatitis and portal cirrhosis do exist as sequelae of acute hepatitis. From July 1946 through December 1948, 100 patients with hepatitis

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Citations
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Journal ArticleDOI

Cirrhosis and primary carcinoma of the liver; changes in their occurrence at the Boston City Hospital, 1897-1954.

TL;DR: During the course of a review of biliary-system neoplasms at this hospital it was noted that the number of primary carcinomas of the liver, both hepatomas and cholangiomas, had significantly increased during the past eight years.
Journal ArticleDOI

Cirrhosis of the liver in infants and children.

TL;DR: It appears that cirrhosis of the liver is not as uncommon a disease in infants and children as had originally been believed and that there are certain features in regard to etiology, incidence, and pathogenesis which are more or less characteristic of this age group.
References
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Journal ArticleDOI

The problem of prolonged hepatitis with particular reference to the cholangiolitic type and to the development of cholangiolitic cirrhosis of the liver.

TL;DR: Excerpt Both sporadic and epidemic jaundice have been generally referred to for many years as "catarrhal" in character.
Journal ArticleDOI

Acute infectious hepatitis in the mediterranean theater: including acute hepatitis without jaundice

TL;DR: During the last four years, cases have been appearing in increasing numbers in both civilians and military personnel in various parts of the world, which has afforded opportunity for the study of large groups of cases and led to a reawakening of interest in the disease among both investigators and clinicians.
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That chronic hepatitis and portal cirrhosis do exist as sequelae of acute hepatitis.