Histopathological spectrum of endometrium in abnormal uterine bleeding
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TLDR
The study revealed the highest incidence of AUB in the perimenopausal age group (41-50 years) and recommended a thorough histopathological workup and clinical correlation are mandatory in cases of abnormal uterine bleeding.Abstract:
Background: Abnormal uterine bleeding (AUB) interferes with the quality of life of an otherwise healthy woman. Until the pathology underlying menorrhagia is, accurately diagnosed, proper therapy is hardly possible. The objective of the study was to analyze different histopathological patterns of endometrium in AUB and observe the incidence of various pathologies in different age groups and their relation to parity.Methods: This two-year prospective studywas done in the department of pathology in atertiary care centre, which included 250 cases of clinically diagnosed AUB patients were evaluated. Histopathological examination of endometrial biopsies and hysterectomy specimens were done, followed by clinical correlation.Results: Out of 250 cases of AUB, Premenopausal bleeding was seen in 216 cases (86.4%) and 34 cases (13.6%) had postmenopausal bleeding. The commonest finding observed in the study was proliferative phase endometrium (37.2%), followed by secretory endometrium (34%) and endometrial hyperplasia (16%). Disordered proliferative endometrium was seen in 2.4% of patients. Endometrial carcinoma was seen in 4 (1.6%) cases. Endometrial hyperplasia was seen mostly in the age group 41-50 years (27 cases). Two cases of endometrial carcinomas were presented after age 60 years.Conclusions: Our study revealed the highest incidence of AUB in the perimenopausal age group (41-50 years). Hence a thorough histopathological workup and clinical correlation are mandatory in cases of abnormal uterine bleeding.read more
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Stereological and histopathological evaluation of doxorubicin-induced toxicity in female rats' ovary and uterus and palliative effects of quercetin and vitamin E.
TL;DR: The findings of this study support the protective role of these dietary supplements in the prevention of DOX-induced toxicity in uterine and ovarian tissues.
Histopathological Correlation of Abnormal Uterine Bleeding
TL;DR: Histopathological examination is the gold standard investigation for patients presenting with AUB and can be treated with hormonal therapy or conservative surgical modalities which greatly reduce the need for hysterectomy.
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Histopathological study of endometrial samples in abnormal uterine bleeding
Prathipaa R,Divya J +1 more
TL;DR: AUB significantly affects the quality life of women and leads to anemia, Hence histopathological examination should be considered which plays a critical role in early diagnosis of endometrial pathology and to provide appropriate gynaecological management.
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Histo-pathological pattern of endometrial biopsy in females with abnormal uterine bleeding: a retrospective study in tertiary care hospital of Haryana
TL;DR: Abnormal uterine bleeding is defined as bleeding from the uterine corpus that is abnormal in regularity, volume, frequency, or duration and occurs in the absence of pregnancy and can be acute and chronic.
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Morphological Pattern of Endometrial Biopsy in Women with Clinical Diagnosis of Abnormal Uterine Bleeding
TL;DR: It is proved that on routine basis endometrial histopathological evaluation is a useful diagnostic measure to determine the underlying cause of abnormal uterine bleeding which ultimately help in accurate treatment.
References
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Study of Endometrial Pathology in Abnormal Uterine Bleeding
Saraswathi Doraiswami,Thanka Johnson,Shalinee Rao,Aarthi Rajkumar,Jaya Vijayaraghavan,Vinod Kumar Panicker +5 more
TL;DR: There is an age specific association of endometrial lesions in perimenopausal women with abnormal uterine bleeding and in reproductive age group, one should first rule out complications of pregnancy.
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Low grade endometrial stromal sarcoma of uterine corpus, a clinico-pathological and survey study in 14 cases.
TL;DR: Clinico-pathological parameters did not significantly differ between patients with and without recurrence, but patients with no myometrial invasion and low mitotic count <= 5/HPF showed longer disease-free survival.
Atypical uterine bleeding-Histopathological audit of endometrium A study of 638 cases
TL;DR: Endometrial curetting and biopsy is an important diagnostic procedure in evaluation of AUB, therefore it is specially recommended in women of the perimenopausal age presenting with AUB to rule out preneoplasia and malignancy.
Journal Article
Histopathological pattern of abnormal uterine bleeding in endometrial biopsies.
TL;DR: Endometrial evaluation is specially recommended in women of perimenopausal and postmenopausal age groups presenting with AUB, to rule out a possibility of any preneoplastic condition or malignancy.
Histopathological Pattern of Endometrial Sampling Performed for Abnormal Uterine Bleeding
TL;DR: It is revealed that secretory and proliferative endometrium are the most common endometrial histopathological patterns identified in endometrian samples obtained for abnormal uterine bleeding in the authors' region.