Journal ArticleDOI
Implications of Agenesis of the Spleen on the Pathogenesis of Conotruncus Anomalies in Childhood
TLDR
The author has shown that early splenic primordia exist at the time of fusion of the A‐V canal cushions and there is a primitive gut mesentery in the left aspect of the dorsal mesogastrium.Abstract:
Six embryos measuring 9–12 mm in greatest length have been shown by the writer to contain early splenic primordia in the left aspect of the dorsal mesogastrium. Their ovulation age is estimated to be 31–36 days. Temporal relations of splenic formation to conotruncus septation and division of the A-V canal have been discussed. This last is divided before septation of the conotruncus is completed. The author has shown that early splenic primordia exist at the time of fusion of the A-V canal cushions. At the same time there is initiation of pulmonary lobation, and there is a primitive gut mesentery.read more
Citations
More filters
Journal ArticleDOI
The anatomy of common aorticopulmonary trunk (truncus arteriosus communis) and its embryologic implications. A study of 57 necropsy cases.
TL;DR: It was found that there appeared to be no such thing as “true” persistent truncus arteriosus in the timehonored sense of persistence of an undivided conotruncal channel, and a revised and simplified classification oftruncus is proposed.
Journal ArticleDOI
Congenital Heart Disease and Other Heterotaxic Defects in a Large Cohort of Patients With Primary Ciliary Dyskinesia
Marcus P. Kennedy,Heymut Omran,Margaret W. Leigh,Sharon D. Dell,Lucy Morgan,Paul L. Molina,Blair V. Robinson,Susan L. Minnix,Heike Olbrich,Thomas Severin,Peter Ahrens,Lars Lange,Hilda N. Morillas,Peadar G. Noone,Maimoona A. Zariwala,Michael R. Knowles +15 more
TL;DR: The prevalence of congenital heart disease with heterotaxy is 200-fold higher in PCD than in the general population (1:50 versus 1:10 000); thus, patients with PCD should have cardiac evaluation.
Journal ArticleDOI
Infections of People with Complement Deficiencies and Patients Who Have Undergone Splenectomy
TL;DR: A review of the role of complement in infectious diseases can be found in this paper, where the authors defined several important functions of complement distinct from that of combating infections, such as limiting complement activation on host cells or facilitating the uptake of antigens or microbes tagged with complement fragments.
Journal ArticleDOI
Syndromes of asplenia and polysplenia. A review of cardiac and non-cardiac malformations in 60 cases withspecial reference to diagnosis and prognosis.
V Rose,T Izukawa,C A Moës +2 more
TL;DR: The study indicated that the cardiac anomalies in polysplenia were less severe than they were in asplenia and therefore the prognosis in the former syndrome is likely to be more favourable.
Journal ArticleDOI
The nomenclature, definition and classification of cardiac structures in the setting of heterotaxy.
Jeffrey P. Jacobs,Robert H. Anderson,Paul M. Weinberg,Henry L. Walters,Christo I. Tchervenkov,Danny Del Duca,Rodney C. G. Franklin,Vera Demarchi Aiello,Marie J. Béland,Steven D. Colan,J. William Gaynor,Otto N. Krogmann,Hiromi Kurosawa,Bohdan Maruszewski,Giovanni Stellin,Martin J. Elliott +15 more
TL;DR: The nomenclature, definition, and classification ofheterotaxy, also known as the heterotaxy syndrome, is reviewed, placing special emphasis on the philosophical approach taken by both the Bostonian school of segmental notation developed from the teachings of Van Praagh, and the European school of sequential segmental analysis.
Related Papers (5)
Syndromes of asplenia and polysplenia. A review of cardiac and non-cardiac malformations in 60 cases withspecial reference to diagnosis and prognosis.
V Rose,T Izukawa,C A Moës +2 more